Sporadic lung cancer Flashcards
1
Q
How does sporadic lung cancer arise?
A
Accumulation of acquired “driver” mutations
2
Q
Testing offered
A
Testing of mutational hotspots in EGFR and testing for EML4-ALK fusion
3
Q
How is EGFR testing performed in these patients?
A
Sequencing
4
Q
How is EML4-ALK testing performed in these patients?
A
FISH
5
Q
What drug treatment can be given if ALK rearrangement present?
A
Crizotinib (TKI)
