Spleen & Pancreas Flashcards

1
Q

Normal appearances of Spleen

A

Size: should not be >12-13cm

Shape: ovoid shape that looks like a half moon
- Convex - superior surface
- Concave - inferior surface
- well defined hilum- splenic Vein & Art* visible

Contour: smooth

Echotexture: very smooth & homogeneous

Echogenicity: mid to low level echoes (should be hyperechoic to liver, sometimes isoechoic, but will be hypoechoic to the pancreas & renal sinus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Spleen: normal variants & anomalies

A

Accessory spleen or Splenunculus:
- found in nearly 1/3 of pop*
- <1 cm diameter or splenic tissue separate from spleen
- commonly seen at hilum w normal splenic appearance
- can be mistaken for lymph node, pancreatic tumour, renal tumour, or adrenal gland mass

Asplenia: absence of spleen

Polysplenia: 2 or more spleens w multiple congenital abnormalities in the abdo & chest

Ectopic accessory spleen:
- small rounded masses of splenic tissue found in various locations other than the LUQ (eg; pancreas or scrotum)

Wandering/mobile spleen:
- due to lax ligaments, spleen can undergo torsion &/or lie in unusual locations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Spleen: indications

A
  • routine abdo US
  • detection/confirmation of splenomegaly
  • portal hypertension invest* inc a spleen assess*
  • masses (1* splenic masses are rare)
  • trauma (rupture &/or haemorrhage)
  • bacterial endocarditis: abscess, infarction (rare)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Spleen S&S

A
  • palpable enlarged spleen in LUQ
  • pain & tenderness LUQ over spleen
  • haemolytic abnormalities (blood tests showing inc/dec WBC or RBC counts)
  • infection: pain, fever, malaise, nausea, vomiting & leukocytosis (eg; abscess)
  • causes of splenomegaly (most common finding in spleen but non-specific)
  • infectious Dx: abscesses, TB, mononucleosis, AIDS & malaria
  • blood Dx: sickle cell anaemia, polycythemia, or thalassaemia

Infiltrative/Neoplastic Dx: lymphoma & leukaemia

Acute trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Splenic cysts

A
  • not commonly seen
  • classified as true cysts (rare) or pseudocysts

True cysts:
- epithelial cell lining
- can be further divided into parasitic (hydatid) & non-parasitic

Pseudocysts:
- from past trauma, infarction, or infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Splenic haemangioma

A
  • most common benign neoplasm of the spleen
  • consists of vascular channels
  • mostly singular but can have multiple

US:
- well-defined echogenic lesion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Splenic calcifications

A
  • can range from small calcifications to large solitary lesions

Splenic granulomatous Dx:
- multiple small clarified granulomas
- infective (eg; splenic TB)
- non-infective (eg; splenic sarcoidosis)
- large calcifications uncommon - may be caused by hydatid cysts, old infarcts, healed abscesses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Splenic trauma

A
  • among the most common trauma-related injuries
  • classified as either penetrating or blunt trauma
  • severity can be objectively classified by a grading system
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Splenic Injury Scale

A

Grade I:
- haematoma - subcapsular, <10% surface area
- lac - capsular tear, <1cm parenchymal depth

Grade II:
- haemat* - subcapsular, 10-50% surface area
- intraparenchymal, <5cm diameter
- lac - 1-3cm parenchymal depth (does Not involve trabecular vessel)

Grade III:
- haemat* - subcapsular, >50% surface area or expanding; ruptured subcapsular or parenchymal haematoma
- lac - >3cm parenchymal depth or involve trabecular vessels

Grade IV:
- lac - involving segmental or hilar vessels & producing major devascularisation (>25% of spleen)

Grade V:
- lac - completely shattered spleen
- vascular - hilar vascular inj* that devascularises the spleen

*Advance 1 grade for multiple injuries up to Grade III

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Splenic rupture

A
  • AKA splenic lac
  • most commonly caused by blunt trauma to abdo (MVA, sports, assault)

S&S
- usually accompanied by other signs of injury form blunt trauma (#ribs, #pelvis, bruising)
- LUQ pain but can be referred to L chest wall/shoulder (Kehr’s sign)

Treatment depends on severity of inj*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Splenic haematoma

A

Assoc* w:
- splenic trauma
- infection
- haematological Dx
- neoplasms (haemangiosarcoma, lymphosarcoma)
- idiopathic

Can be subcapsular or within parenchyma

Can lead to splenic rupture esp. post trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Splenic abscess

A
  • most often seen as a complication of infective endocarditis
  • can be: bacterial, fungal, or parasitic origin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Splenic infarct

A
  • blood supply to the splenic artery or one of its branches is compromised
  • necrosis of supplied tissue
  • most commonly caused by thromboembolic Dx & infiltrative haematologic Dx
  • can also occur as result of trauma, torsion if splenic artery in ‘wandering spleen’, post surgery (pancreatectomy, liver Tx)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pancreas: normal appearance

A

Shape: dumbbell, tadpole, sausage & comma-shaped

Exhogenicity: Mod echogenic but hyperechoic to adj* liver
- can be isoechoic to liver
- echogenicity inc* w age due to fatty changes

Parenchymal echotexture:
- generally homogenous, but can appear heterogeneous if there is a lot of intralobular fat
- considered more ‘coarse’ than liver

Contour: altho* it does NOT have a capsule, it has a smooth, curvilinear contour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Echogenicity ladder

A

Renal sinus => pancreas => spleen => liver => renal cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pancreas: normal measurements

A

Head & Uncinate: 2-3cm AP

Neck: 1.5-2.5cm AP

Body: 2-3cm AP

Tail: 1-2cm AP

Total length: 12-18cm

Pancreatic duct: <2mm at Body

17
Q

Pancreas US: indications

A
  • standard organ assessment for upper abdo US
  • assoc* w biliary tree assess* (eg; CBD)
  • ? Obstruction from stone/neoplasm
  • acute & chronic epigastric &/or RUQ pain
  • jaundice
  • weight loss
  • palpable epigastric mass
18
Q

Pancreatic eco functions

A

Lipase => digests fats
Amylase => digests carbs

Trypsin, chemotrypsinogen, carboxypeptidase => digests proteins

Nucleases => digests nucleic acids

19
Q

Pancreatitis

A
  • inflamm* of pancreas

Classifications:
- acute or chronic
- mild, mod, or severe

Causes
- biliary Dx
- alcohol abuse
- trauma
- ulcers
- idiopathic

20
Q

Acute pancreatitis S&S

A
  • abdo pain
  • N&V
  • Hx gallstones
  • alcoholism
  • fever
  • inc* enzymes
  • inc* leukocytes
  • abdo distension
  • jaundice
  • malabsorption
21
Q

Chronic pancreatitis

A
  • results from recurrent attacks of acute pancreatitis
  • causes destruction of pancreatic parenchyma
  • assoc* w chronic alcoholism or biliary Dx

Pts may also have;
- pseudocysts (25-40%)
- dilated CBD
- thrombosis of splenic vein w extension into the portal vein
- inc* risk of Pt developing pancreatic CA

Defining features:
- double duct sign (dilated pancreatic & CBD
- calcifications noted in one or both ducts

22
Q

Pancreatic labs tests

A

Serum amylase:
- normal = 25-125 U/L
- inc* w acute pancreatitis, pancreatic pseudocyst

Urine amylase:
- remains inc* longer than serum Amy in episodes of acute pancreatitis

Serum Lipase:
- normal = 10 to 140 U/L
- remains elevated for longer periods (up to 14 days)
- inc* w pancreatitis, obs*of the pancreatic duct, pancreatic carcinoma

Glucose:
- normal = <100mg fasting & <145mg 2 hrs post prandial
- inc* w severe diabetes mellitus or NIDDM, & over activity of several endocrine glands
- dec* w tumours if the islets of Langerhans in the pancreas

23
Q

Pancreatitis: complications

A
  • pancreatic & para-pancreatic fluid collections develop
  • fluid collections may resolve spontaneously, those that do Not are recognised as pseudocysts
  • pseudocysts are always acquired; result from trauma to gland or from acute/chronic pancreatitis
  • pseudocysts develop in 10-20% w acute pancreatitis
  • pseudocysts develop 4-6wks after onset of pancreatitis
24
Q

Pancreatic adenocarcinomas

A
  • CA in lining or inner surface of the pancreas & usually has secretory properties
  • involved exocrine portion of the gland (distal epithelium)
  • most common primary neoplasm of pancreas
  • accounts of >90% of all malignant pancreatic tumours
  • accounts for approx 5% of all CA deaths & 4th most common cause of CA related mortality after, lung, breast & colon CA
  • rare before the age of 40th
  • majority of Pts >60yrs
  • poor prognosis; median survival time of 2-3 months & 1 yr survival rate of only 8%