Spleen Flashcards
When does the spleen begin to develop in embryologic development?
5th week of gestational age
What role does the fetal spleen play during development?
producing red and white blood cells
When does the spleen begin hematopoiesis?
11th week of gestational age
When do the lobulations of the fetal spleen smooth out?
5-6 weeks
Where does the fetal spleen originate from?
mesoderm cells in the dorsal mesogastrium
production of blood cells (RBCs, WBCs, platelets)
hematopoiesis
What is the single largest mass of lymphoid tissue in the body?
spleen
T or F: Since the spleen is a component of the immune system, removal can cause adverse side affects
False.
It can be removed without adverse side affects
T or F: the spleen is often affected by a systemic disease process and is rarely the primary site of disease
True.
RBC
erythrocyte
process of making RBCs
erythropoiesis
a cell that engulfs and consumes foreign material and debris
phagocyte
removal of worn out and abnormal RBCs and platelets from the bloodstream
phagocytosis
the spread of an infection from its initial site to the bloodstream
sepsis
Donning a gown, mask, and gloves because the pt is immunocompromised because they have a low number of neutrophils
neutropenic precautions
iron containing, oxygen carrying pigment of RBCs
hemoglobin
% of RBCs within your blood volume
hematocrit
located medially in the spleen; where the vasculature enters/exits
splenic hilum
has the responsibility of phagocytosis; found in the spleen, liver, lymph nodes, alveoli, brain, blood vessels, mucous membranes
reticuloendothelial system
where worn-out RBCs and blood borne pathogens are destroyed; consists of splenic sinuses and splenic cords
red pulp
where immune system functions take place; consists of lymphatic tissue containing lymphocytes and monocytes that continually digest harmful pathogens entering the blood stream
white pulp
non-penetrating trauma
blunt force trauma
The spleen is a __1___ organ covered by a ___2___ except where vessels enter/exit at the hilum.
- peritoneal
- peritoneum
T or F: the spleen has a strong capsule
False.
The spleen does not have a strong capsule; making it fragile and susceptible to injury
What is the length of the spleen?
8-13 cm
What is the height (AP) of the spleen?
7-8 cm
What is the width of the spleen?
3-4 cm
What is the normal volume of the spleen?
60-200 mL
What is the splenic index?
107-314
What are supporting ligaments of the spleen?
- splenorenal ligament
- phrenicocolic ligament
- gastrosplenic ligament
The spleen lies in which region and quadrant?
LT hypochondrium/LUQ
The spleen lies ______ to the stomach and pancreas tail?
posterolateral
The spleen lies _______ to the LT colic flexure?
posterior
The spleen lies _______ and _______ to LK?
superior, lateral
The spleen lies ________ to the LT hemidiaphragm and LT lung?
anterior
The spleen lies _______ to ribs along dorsal abdomen?
anterior
courses horizontally along the superior border of the tail of the pancreas; tortuous; SUP/ANT to splenic vein
splenic artery
courses horizontally along the inferior border of the tail of the pancreas; part of portal venous circulation?
splenic vein
What is the primary function of the spleen?
Remove…….from circulation
- old blood cells
- debris
- pathogens
- foreign substances
The spleen is a soft organ with elastic properties that allow it to distend; helps it act as a _______________?
blood reservoir
The spleen contains ________ of connective tissue which divides the spleen into lobules?
trabecula
What 2 tissues are within the lobules of the spleen?
- white pulp
- red pulp
Performs lymphatic function of spleen?
white pulp
Performs phagocytic function spleen?
red pulp
consists of splenic sinuses alternating with splenic cords (microscopic)?
red pulp
consists of Malpighian corpuscles (a type of lymphoid tissues that acts as a filter)?
white pulp
Red or white pulp contains RBCs and phagocytes?
red pulp
Produces antibodies, lymphocytes, and monocytes to aid in immune response?
white pulp
removing irregular RBCs from the blood stream?
culling