Spinal Surgery- Principles Flashcards

1
Q

Why do the effects of aspirin take 10 days to reverse?

A

Aspirin irreversibly blocks COX enzymes.

Plts have no nucleus and can thus not replace the enzymes.

The average life of a plt is 10/7, hence it takes 10/7 for the entire plt population to be replaced.

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2
Q

How quickly can normal haemostasis be demonstrated in the context of antiplatelets?

A

Normal haemostasis can be demonstrated with as few as 20% normal plts and some studies now suggest the effects of aspirin can wear off after 2-4/7.

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3
Q

Prone positioning for posterior cervical approaches?

A

Prone

Mayfield

Chin flexed and head lifted to maximise the space between the back of the shoulders and the occiput.

It is important to ensure the chin is not touching the operating table which will often be in a head-up position.

The arms are usually beside the patient.

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4
Q

Prone positioning for lumbar spinal surgery?

A

Maybe on a frame or a spinal operating table that flexes the patient’s lumbar spine.

Important to get the width of the supports correct to prevent abdominal pressure (which impairs venous return).

Some surgeons use the knee-elbow position though care must be taken to avoid nerve palsies.

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5
Q

Key considerations w.r.t. prone positioning?

A

Neck not overextended

Axillae not compressed.

No pressure on the eyes

No compression of external male genitalia.

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6
Q

Positioning for anterior cervical spine surgery?

A

Horseshoe

Rolled towel behind the shoulders to aid neck extension.

Pad the eyes.

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7
Q

Lateral positioning

A

Used for extreme lateral interbody fusion procedures

True lateral and AP views must be obtained to avoid parallax errors.

The surgical plane is perpendicular to sagittal which allows abdominal contents to fall forwards.

Neural monitoring, especially for the L4/5 level, is recommended to avoid injury to lumbar plexus

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8
Q

Contraindications to extreme lateral interbody fusion approach

A

Anomalous vascular anatomy

Peritoneal scarring

Spondylolisthesis greater than grade II

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9
Q

What approach to interbody fusion provides better access to L5/S1?

A

Anterior as the XLIF approach is limited by the iliac crests

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10
Q

Complications of ALIF

A

Vascular injury

Visceral damage

Retrograde ejaculation

Sympathetic disruption

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11
Q

Def: parallax error

A

The error/displacement caused in the apparent position of the object due to the viewing angle that is other than the angle that is perpendicular to the object.

Minimised by keeping needles close to the structure being marked and that the XR machine is correctly positioned.

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12
Q

SSEPs

A

Sensory stimulus over a nerve measured with percutaneous electrodes over the sensory cortex

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13
Q

MEPs

A

Measured from a muscle after a stimulus is given to the motor cortex

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14
Q

SSEP threshold suggestive of dorsal column insult intra-operatively

A

10% increase in latency from baseline or a 50% reduction in amplitude.

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15
Q

MEP threshold suggestive of anterior corticospinal tract injury

A

Any significant change in waveform considered significant SC insult as motor potentials are considered “all or nothing” by many neurophysiologists

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16
Q

Fusion rates for ACDF

A

Around 90%

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17
Q

What must happen for metalwork to succeed in spinal surgery

A

Bony fusion.

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18
Q

Bony fusion in traumatic SC surgery vs MSCC

A

More likely to occur in trauma, therefore in MSCC the construct must be longer.

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19
Q

Factors promoting bony fusion

A

Decortication of bone surfaces

Adding autograft (iliac crest)

Allogenic cancellous or decorticated bone

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20
Q

Factors inhibiting bone fusion

A

NSAIDs odds ratio of 3.0 for non-union

Smoking also inhibits

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21
Q

Recombinant bone morphogenic protein 2

A

Promotes osteoblast differentiation and is effective in promoting spinal fusion.

Safety concerns include include implant displacement, subsidence, infection, urogenital events, retrograde ejaculation, radiculitis, ectopic bone fromation, osteolysis and poorer global outcomes.

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22
Q

Use of internal fixation in spinal surgery?

A

Correction of deformity:

Kyphosis, scoliosis

Stabilisation:

Fracture, dislocations, malignant and degenerative pathology

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23
Q

General principle of screw-rod fixation systems

A

Utilise pedicles and lateral masses as fixation points

Allows instrumentation of the sacrum

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24
Q

Parts of the screw

A

The section that contains the thread

Head

Variation of different types of screws is based on the type of head, the type of interface between the screw head and shaft, whether the shaft is fully or partially threaded and if the shaft is fenestrated.

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25
Q

What are the two types of interface between the screw head and shaft?

A

Monoaxial

Polyaxial

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26
Q

Monoaxial screws

A

Do not allow movement between the screw head and the shaft

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27
Q

Use of monoaxial screws

A

For deformity correction

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28
Q

Polyaxial screws

A

Joint with a spherical head enclosed in a housing which allows the screw head to move in relation to the shaft

Allow the surgeon some flexibility in connecting the screws to rods.

Fail at the head-shaft interface rather than along the shaft or rod

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29
Q

Subdivisions of polyaxial screws

A

Uniplanar- allow movement in the cranial or caudal plane only

Multiplanar- allow movement in multiple planes

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30
Q

Subdivisions of multiplanar polyaxial screws

A

Biased- allow angulation up to 55 degrees in one direction

Non-biased- allow up to 30 degrees of angulation in each direction

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31
Q

Types of shaft design

A

Fully threaded

Smooth shank screws

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32
Q

Features of smooth shank screws

A

10mm unthreaded segment and are used in the C1 lateral mass where the smooth shank is designed to prevent the thread irritating the C2 nerve root.

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33
Q

Lag screws

A

Unthreaded segment and a distal half that is threaded

Used in odontoid peg fixation where the thread sits in the peg and the shaft in the C2 vertebra

Tightening the screw compresses the fracture thus improving bony fusion.

Lag screw sits flush

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34
Q

Features of fenestrated screws

A

A hole down the middle which enables K-wire insertion to guide screw placement or the insertion of cement down the screw

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35
Q

Def: pitch of a screw

A

Distance travelled by the screw in one 360 degree turn

Fine pitched screw travels a short distance, used in cortical bone and generally has a higher pull out strength

Coarse screw travels further with each turn, requires less force to insert and is used in cancellous bone.

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36
Q

Rescue screws

A

Can be used where a screw has a poor hold.

Usually has a wider diameter and coarser pitch.

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37
Q

Types of screw tips

A

Rounded- need tapping to start the screw off

Self-tapping- has cutting flutes at the tip but still requires a pilot hole

Self-drilling- sharp and not requiring pilot hole.

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38
Q

Types of plates

A

Locking or non-locking/dynamic plates

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39
Q

Locked plates

A

The screw is held in the plate so that the angle of the screw to the plate is fixed

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40
Q

Dynamic plates

A

Allow some movement as the fracture settles

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41
Q

Forces resisted by screw/plate or screw/rod vs cages

A

Scfew/plate- distraction

Cage- compression

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42
Q

Advantages of minimal access surgery

A

Less pain

Less analgesia requirements

Shorter duration of stay

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43
Q

Disadvantages of minimally invasive spine

A

May be more difficult

Risk of incorrect port placement

More XR exposure

Equipment is often extensive

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44
Q

Prevention of infection in spinal surgery

A

Razer rather clippers for hair removal

Laminar flow theatres (no RCTs)

Gent scrub

Double gloving

Prophylactic antibiotics.

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45
Q

VTE and spinal surgery

A

Early mobilsation, good hydration, compression stockings.

LMWH

46
Q

Incidence of post-op compressive epidural haematoma

A

0-1%

47
Q

Component of the vertebral column

A

24 mobile vertebrae

C7

T12

L5

Fused vertebrae

S4-5 + C4

48
Q

What limits movement of mobile vertebrae?

A

Intervertebral discs

Paired posterior synovial facet joints

Intervertebral ligaments

Paraspinal muscles

49
Q

Diurnal variation in length of vertebral column

A

2cn

50
Q

Age-related loss of vertebral column length

A

Related to dehydration fo the inrevertebral dsiscs

51
Q

Primary roles of the vertebral column

A

Protect the spinal cord

Provide stability and mobility

To control the transmittance of movement from the upper and lower extremities

52
Q

Curves of the spine

A

Cervical lordosis

Thoracic kyphosis

Lumbar lordosis

Sacral kyphosis

53
Q

Which part of the vertebral column is responsible for the majority of the load transfer fo the spine

A

Anterior column (vertebral bodies and intervertebral discs)

54
Q

Typical articulation between two prevertebral vertebrae

A

Two posterior intervertebral facet joints between the inferior and superior articulating facets and the intervertebral disc.

This creates three points of articulation between each vertebra

55
Q

The trend in width and depth of vertebra

A

They increase from cranial to caudal, corresponds with increased compressive strength due to the greater axial loads experienced in the more caudal segments.

56
Q

Microscopic arrangement of the vertebral body

A

Outer cortical layer

Inner cancellous bone with the microarchitecture adapted so that the trabeculae are orientated along the lines of application of load to provide resistance to dynamic loading.

57
Q

How is the C1 vertebra atypical?

A

No vertebral body

Anterior arch with odontoid peg directly behind it

Flattened posterior arch with a small midline posterior tubercle

The articular processes are medially orientated to permit both flexion/extension and rotational movements

58
Q
A
59
Q

Features of C2

A

Odontoid peg- a superior bony extension of the vertebral body

Has the largest spinous process in the spine.

60
Q
A
61
Q

Subaxial vertebrae?

A

C3-7

Uniform morphology

In this region, the uncinate processes on the superior anterolateral aspects of the vertebral bodies articulate with a corresponding articulation of the vertebral body above. This uncovertebral joints aids rotation in the cervical spine

62
Q

Features of thoracic vertebrae

A

Uniform morphology with a long inferiorly angulated spinous process and vertically orientated facet joints

There are costovertebral joints from T1 to T12 that provide articulation between the vertebra and corresponding rib.

There are also rib articulations on the transverse processes from T1 to T10.

In this region, the ribs, sternum and intercostal structures provide extra stability.

63
Q

Orientation of lumbar facet joints

A

Sagittal plane

64
Q

Which cervical vertebra does not have a bifid spinous process?

A

C7

65
Q

Structure of intervertebral disc

A

Found between the inferior and superior endplates of the vertebrae above and below.

Has a central nucleolus pulposus with a surrounding annulus fibrosis.

Acts to transmit load, allow movement, provide stability

66
Q

Composition of the nucleus of the intervertebral disc

A

Comprised of mostly water (80-90%)

Type 2 collagen and multiple hydrophilic proteoglycans.

The interaction between the annulus fibrosis and these proteoglycans leads to a unique hydrostatic structure.

When the disc is loaded in compression water seeps out and the height of the disc is reduced, but the turgidity of the nucleus allows the transmission of the force to the obliquely orientated fibres in the multiple lamellae of the annulus.

67
Q

Which fibres connect the annulus fibrosis to the cortical bone of the vertebral body?

A

Sharpey’s fibres

68
Q

What happens to intervertebral discs with age?

A

The ability to resist axial compression.

The proteoglycan composition of the nucleus changes with a decrease in water retention.

There is a loss of disc height

Disc bulbing is often seen.

Asymmetric loading of the disc in a pathological curve of the spine leads to migration of the nucleus pulposus to the convex side causing disc bulging (not herniation).

69
Q

Posterior elements of the spinal cord

A

Laminae

Spinous processes

Bilateral facet joints

70
Q

Zygapophyseal joints=

A

Facet joints

71
Q

Features of spinal facet joints

A

Synovial plane joints between the superior and inferior articular processes of the lumbar vertebrae

In the cervical cord, they are orientated coronally allowing flexion-extension, lateral bending and rotation.

In the lumbar spine, they are orientated sagittally, resisting rotational movement but allowing flexion/extension.

72
Q

Why is there a lower incidence of anterior subluxation at L5/S1?

A

The facet joints have a more coronal orientation.

Degenerative spondylolisthesis is thus more common at L4/5.

73
Q

Where is the spinal canal most narrow?

A

T7

74
Q

What structures can contribute to stenosis of the spinal canal?

A

Bulging of the annulus due to dehydration

Overgrowth of facet joints due to OA

Folding in of the ligamentum flavum due to disc height

Causing the classical “Trefoil” appearance of the spinal canal.

75
Q

What connects the anterior and posterior elements of the vertebral canal?

A

Pedicles

76
Q

Features of the pedicles

A

Signficant variation in pedicle size and orientation seen through the spine.

Smallest at T4

77
Q

Ligaments that provide stability to the spine

A

Anterior and posterior longitudinal ligaments

Interspinous ligaments

Ligamentum flavum

Intertransverse ligaments

Capsular ligaments

78
Q

Movement resisted by interspinous lkigaments

A

Flexion

79
Q

Movement resisted by anterior longitudinal ligament?

A

Strong attachment to the vertebral bodies but not the intervertebral discs.

Rists extnesion

80
Q

Attachments of the ALL

A

Skull base to sacrum

81
Q

Posterior longitudinal ligament

A

Clivus to coccyx

Provides limited resistance to flexion.

Made up of two layers

Attached to the intervertebral discs.

Constrains herniation of the nucleus pulposus

82
Q

Extent of the ligamentum flavum?

A

C2 to S1

Close to the axis of rotation.

83
Q

Why is the ligamentum flavum yellow?

A

Due to its high elastin content

84
Q

What is the significance of the relatively high elastin content of the ligamentum flavum?

A

Prevents the ligament buckling in extension and narrowing the spinal canal diameter

85
Q

What is the tectorial ligament?

A

Cranial extension of the PLL

86
Q

Where is the ligamentum flavum deficient?

A

In the midline

87
Q

What are the capsular ligaments?

A

Capsule ligament enclosing the spinal facet joints,

88
Q

What are the components of the cruciate ligament?

A

It consists of the transverse ligament of the atlas, along with additional fibres above and below.These fibres are also known as “longitudinal bands

89
Q

What is the importance of the transverse ligament of atlas?

A

Significant role in prevent C1/2 subluxation

90
Q

Apical ligament of axis?

A

Runs from the tip of the odontoid peg to the skull base

91
Q

Alar ligament

A

Run from the sides of the odontoid peg to the skull base

92
Q

Ligamentous structures stabilising the cranio-cervical junction?

A

Cruciate ligament (transverse ligament and superior and inferior longitudinal bands)

Apical ligament

Alar ligaments

Accessory part of tectrorial membrane

Atlanto-occipital membrane

93
Q

Causes of congenital variation in spinal anatomy

A

Failure of segmentation or formation.

94
Q

Scoliosis results from what?

A

Three dimensional deformity.

95
Q

Klippel-Feil Syndrome

Triad

A

Low posterior hairline

Short “webbed” neck

Limited cervical range of movement

Associated renal/congenital cardiac disease/ brainstem abnormalities/ cerbical scoliosis/ Sprengel’s deformity

96
Q

Sprengel’s deformity

A

Sprengel’s deformity (also known as high scapula or congenital high scapula) is a rare congenital skeletal abnormality where a person has one shoulder blade that sits higher on the back than the other.

97
Q

Pathophysiology of Klippel-Feil syndrome

A

Failure of formation or segementation of the cervical somites at 3-8/40.

98
Q

Categorisation of function othe spine

A

Static (protection of SC)

Dynamic (provision of stability and mobility, to control transmittance of movement to the upper and lower extremities)

99
Q

Advice to patients with Klippel-Feil

A

Aim for conservative Mx unless spinal instability or neurological deterioration

Avoid collision sports

Frequently develop degenerative cervical conditions

100
Q

Normal flexion/extension at C0/C1

A

15 degrees

101
Q

Normal flexion/extension at C1/2

A

10 degrees

102
Q

Normal flexion extension in the subaxial C-spine

A

7 degrees in the upper

20 in the lower.

103
Q

Flexion-extension in lumbar spine

A

Increases caudally up to 20 degrees at L5/S1

104
Q

What prevents flexion in the thoracic spine?

A

Splinting by the ribs

105
Q

Rotation in the ccervical spine

A

45 degrees at C1/2

Between 7 and 10 degrees at each level.

No rotation at Co

106
Q

At which level of the spine is there no lateral flexion

A

C1/2

107
Q

What is the functional spinal unit?

A

Two adjacent vertebrae with the intervening disc and associated ligaments.

It is the smallest anatomical spinal segment that can be considered to exhibit the biomechanical characteristics of the whole spine.

108
Q

Hooke’s law

A

For small displacements, the size of deformation is proportional to the force applied.

109
Q

What is the zone of plastic deformation

A

The point beyond the elastic limit at which a material totally recovers when a stress is applied.

110
Q

Coupled movements in the spine

A

Often coupled so that movements along one axis leads to a movement along another.

This is mostly due to orientation of the facet joints e..g in the cervical spine where lateral bending results in rotation of the spinal processes away from the concavity of the curve.

111
Q

Def: Clinical stability of the spine

A

Described by White and Panjabi

`the ability of the spine under physiological loads to limit patterns of displacement so as not to damage or irritate the spinal cord or nerve roots and in addition, to prevent incapacitating deformity or pain due to structural changes.

112
Q
A