spinal cord development Flashcards

1
Q

where does the spinal cord end

A

conus medullaris

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2
Q

which layer is the outermost of the 3 primary germ layers

A

ectoderm

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3
Q

which layer is the root of all neural tissue

A

ectoderm

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4
Q

which layer is the middle of the 3 primary germ layers

A

mesoderm

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5
Q

which layer forms much of the bone and musculature

A

mesoderm

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6
Q

what layer is the innermost of the 3 primary germ layers

A

endoderm

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7
Q

what layer forms much of the viscera

A

endoderm

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8
Q

the process of neural tube formation

A

neurulation

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9
Q

what is the precursor structure to the CNS

A

neural tube

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10
Q

where are the neuropores found

A

at each end of the neural tube

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11
Q

somites arise from

A

mesoderm

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12
Q

what is affected in all forms of spina bifida

A

somites

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13
Q

notochord cells go on to form

A

intervertebral discs

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14
Q

what cells differentiate to form the Pia and arachnoid mater

A

neural crest cells

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15
Q

what is the dura mater formed from

A

mesoderm

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16
Q

which grows first: axial skeleton or CNS?

17
Q

any of a series of conditions caused by failure of the neural tube to close

A

neural tube defects

18
Q

2 most common neural tube defects

A

spina bifida
ancephaly

19
Q

central closure issue

A

cranioarachischisis
encephalocele

20
Q

anterior closure issue

A

anencephaly
iniencephaly

21
Q

posterior closure issue

A

spina bifida

22
Q

closer to which neuropore has a higher risk of fatality

A

closer to anterior neuropore

23
Q

which neural tube defects are 100% fatal

A

ancephaly
cranioarachischisis
iniencephaly

24
Q

which neural tube defect is 50-100% fatal

A

encephalocele

25
neural tube defect with meninges/neural tissue exposure
open NTD
26
neural tube defect with skin intact
closed NTD
27
which subtype of spina bifida can be open or closed
meningocele
28
which subtype of spina bifida is the most common and least debilitating form
occulta
29
out pouching of the meningeal layers WITHOUT neural tissue
meningocele
30
out pouching of the meningeal layers WITH neural tissue
myelomeningocele
31
myeloschisis
out pouching of neural tissue without meningeal covering
32
examples of closed NTD
lipomyelomeningocele lipomeningocele tethered cord
33
which NTD is not affected by supplementation of folate
lipomyelomeningocele
34
what does CT measure
density
35
what does MRI measure
RF signal form protons
36
STIR MRI is beneficial for
fat suppression
37
in STIR MRI water (edema) is
bright
38
in FLAIR MRI, you have increased visibility near
CSF-brain borders