spinal cord development Flashcards

1
Q

where does the spinal cord end

A

conus medullaris

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2
Q

which layer is the outermost of the 3 primary germ layers

A

ectoderm

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3
Q

which layer is the root of all neural tissue

A

ectoderm

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4
Q

which layer is the middle of the 3 primary germ layers

A

mesoderm

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5
Q

which layer forms much of the bone and musculature

A

mesoderm

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6
Q

what layer is the innermost of the 3 primary germ layers

A

endoderm

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7
Q

what layer forms much of the viscera

A

endoderm

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8
Q

the process of neural tube formation

A

neurulation

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9
Q

what is the precursor structure to the CNS

A

neural tube

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10
Q

where are the neuropores found

A

at each end of the neural tube

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11
Q

somites arise from

A

mesoderm

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12
Q

what is affected in all forms of spina bifida

A

somites

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13
Q

notochord cells go on to form

A

intervertebral discs

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14
Q

what cells differentiate to form the Pia and arachnoid mater

A

neural crest cells

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15
Q

what is the dura mater formed from

A

mesoderm

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16
Q

which grows first: axial skeleton or CNS?

A

CNS

17
Q

any of a series of conditions caused by failure of the neural tube to close

A

neural tube defects

18
Q

2 most common neural tube defects

A

spina bifida
ancephaly

19
Q

central closure issue

A

cranioarachischisis
encephalocele

20
Q

anterior closure issue

A

anencephaly
iniencephaly

21
Q

posterior closure issue

A

spina bifida

22
Q

closer to which neuropore has a higher risk of fatality

A

closer to anterior neuropore

23
Q

which neural tube defects are 100% fatal

A

ancephaly
cranioarachischisis
iniencephaly

24
Q

which neural tube defect is 50-100% fatal

A

encephalocele

25
Q

neural tube defect with meninges/neural tissue exposure

A

open NTD

26
Q

neural tube defect with skin intact

A

closed NTD

27
Q

which subtype of spina bifida can be open or closed

A

meningocele

28
Q

which subtype of spina bifida is the most common and least debilitating form

A

occulta

29
Q

out pouching of the meningeal layers WITHOUT neural tissue

A

meningocele

30
Q

out pouching of the meningeal layers WITH neural tissue

A

myelomeningocele

31
Q

myeloschisis

A

out pouching of neural tissue without meningeal covering

32
Q

examples of closed NTD

A

lipomyelomeningocele
lipomeningocele
tethered cord

33
Q

which NTD is not affected by supplementation of folate

A

lipomyelomeningocele

34
Q

what does CT measure

A

density

35
Q

what does MRI measure

A

RF signal form protons

36
Q

STIR MRI is beneficial for

A

fat suppression

37
Q

in STIR MRI water (edema) is

A

bright

38
Q

in FLAIR MRI, you have increased visibility near

A

CSF-brain borders