Spinal Anesthesia 6/1 Flashcards
Fentanyl dose?
1.5 - 3 mcg/kg
How do you prevent pruritis associated w/ neuraxial opioids?
- minimize morphine dose to <300mcg
- Ondansetron (Zofran) 4mg IV
- Nubain 2.5-5mg IV
How do you treat pruritis associated w/ neuraxial opioids?
- Benedryl 25-50mg IV
- Naloxone 0.1mg IV (“best”)
- Buprenex (mixed agonist/antagonist
How much epi is considered to be in an “epi wash?”
0.2-0.3mg
How much Phenylephrine (neosynephrine) is considered to be in a “neo wash”?
2-5 mg
What LA when combined w/ a vasoncstrictor is considered to have a profound increase?
Tetracaine
What kind of change do you see when epi is added to Lidocaine and bupivacaine?
Bupivacaine / Lidocaine have a variable increases
How do you prevent the five and dime reflex?
Glycopyrrolate (Robinol) (doesnt cross BBB)
prevents bradycardia!
What’s the dose of clonidine added to spinal anesthetic?
Precedex?
- Clondine: 15-45 mcg
- Precedex: 3 mcg
Provide the subarachnoid/intrathecal doses for the following opiods:
* Morphine
* Fentanyl
* Sufentanil
- Morphine 0.1-0.4 mg
- Fentanyl 10-25 mcg
- Sufentanil 2.5-10 mcg
Describe the factors that contribute to a differential block. Does this apply to Epidural or Spinal?
BOTH EPIDURAL AND SPINAL ARE DIFFERENTIAL
* Nerve fibers differ in sensitivity to LA
* Gradual and segmental block of fibers when exposed to LA
* Smaller diameter axons are MORE sensitive
* Unmyelinated fibers are more sensitive that myelinated
Can a SAB have a segmental block? Does Epidural have segmental block?
NO. NEVER. ONLY EPIDURAL HAS SEGMENTAL
List the clinical progression of the differential blockade of nerve fibers and include function
B, C, A-(delta,gamma,beta, alpha)
- B-Fibers (sympathetic)
- C and A-Delta (pain and temp)
- A gamma (motor tone)
- A-beta (touch/pressure)
- A-alpha (loss of motor function/proprioception)
What order does the differential blockade recover?
The oppositve of the onset
e.g. A-Alpha (motor and proprioception) is first to recover
C-section requires a sensory block at what dermatome level ?
T4 (nips)
Motor blockade is how many levels below sensory block?
2
What are the cardioaccelerator nerves
T1-T4
Elimination of LA from SAB
Would a hydrophilic or lipophilic drug have a longer DOA ?
Hy
Lipophilic lasts longer (ex. Bupivacaine)
Lipophilic drugs like to hang out in the epidural fat
Factors affecting LA distribution and block height in SAB
Most important drug factors
- Dose
- baricity
Factors affecting LA distribution and block height in SAB
Most important patient factors
- CSF volume
- Advanced Age
- Pregnancy