Spinal And Autonomic Nerves Flashcards
What is the disease in the brain called?
Encephalopathy
What is a disease of the spinal cord called?
Myelopathy
What is a disease in the peripheral nerves called?
Peripheral neuropathy
Peripheral neuropathies differ from CNS encephalopathgies and myelopathies by the presence of:
- hyporeflexia and hypotonia
- denier action atrophy
- unilateral (!) motor and/or sensory deficits
- normal. Function cranial and caudal to nerve lesion site
Where would bilateral motor and/or sensory deficits lesion be located?
Spinal cord/myelopathy
What does a spinal nerve consist of? (4)
- roots
- main trunk
- 4 primary branches
- peripheral branches of the primary branches
Where are roots located?
Within the vertebral canal
What are the sensory afferent region/structures of the spinal roots?
Dorsal roots and spinal dorsal root ganglia
Dorsal roots have what type of function?
Afferent/sensory
What are the motor efferent structures of the spinal roots?
Ventral roots
Afferents have what type of function?
Sensory
Efferents have what type of function?
Motor
Where is the main trunk of the spinal nerves located?
Intervertebral foramen
What is the spinal nerve formula of the horse?
C8 T18 L6 S5 Cd7
What is the spinal nerve formula for the cow?
C8 T13 L6 S5
How is the spinal nerve formula determined?
Total number of vertebrae plus 1 cervical
Where does the 1st cervical nerve emerge?
Though the lateral vertebral foramen of atlas
Where does the 2nd cervical nerve emerge IN THE DOG?
Through the intervertebral foramen between the 1st and 2nd vertebrae.
Where does the 2nd cervical nerve emerge from IN THE HORSE?
Though the lateral vertebral foramen of the axis
Where does the 8th cervical nerve emerge? (Between who?)
Runs through the intervertebral foramen between the 7th cervical and 1st thoracic vertebrae
What does a laminectomy entail?
Take thee top off..of the spinal n. to see underneath
What are the 4 Branches of the main trunk of the spinal nerve?
- dorsal
- ventral
- meningeal
- communicating
What does the dorsal primary branch supply?
The dorsal axial/epaxial and skin over dorsal/dorsalateral body area
Who is the largest primary branch of the spinal nerve?
Ze ventral primary branch!!!!
What does the ventral primary spinal nerve innervate?
- Hypaxial muscles
- thoracic and pelvic limbs
- skin over these regions
The brachial plexus is associated with what primary branch?
Does it synapse here?
Ventral primary branch
No
What is an example of a named nerve coming out of the brachial plexus?
Radial nerve
What nerves/branches form the lumbosacral region?
Ventral branches of L4-S4
What plexus supplies the pelvic limb and perineal region?
What primary branches are associated with it?
Lumbosacral plexus
Ventral branches of L4-S4
Who is the smallest branch of the primary branches of the spinal nerve?
Meningeal branch
What is the meningeal primary branch involved with/what do they detect?
Noceceptive signals of back injury
Where does the communicating branch run to/with?
Runs with the sympathetic trunk and chain ganglia
What does the communicating branch do?
Visceral function of autonomic nervous system
What do somatic autonomic nerves innervate?
Body wall, skin, subQ tissue, skeletal muscle, joints, tendons, etc
What does the visceral peripheral nerves innervate?
Internal organs, smooth muscle, cardiac muscle, and glands
What do cutaneous nerves innervate?
Skin, smooth muscle around blood vessels (they contain visceral efferent nerve fibers)
half of the nerves of the Muscle/motor nerves are muscle _________from muscle propriooceptors.
Afferents
Where does a mixed nerve go?
Skin AND muscle
What is an example of a mixed nerve?
Femoral nerve
What are the functional components of the cutaneous branches of the spinal nerves?
somatic afferents
visceral afferents
visceral efferents
What structures are the visceral afferents and efferents associated with?
blood vessels (receptors and the smooth muscle surrounding them)
Visceral efferents are in what type of fiber? (pre/postG; sym/parasym)
Where are their cell bodies?
postganglionic sympathetic fibers running in chain ganglia
What is a cutaneous area?
area of skin supplied by a given cutaneous nerve
What is an example of a cutaneous nerve that innervates a cutaneous area on the hind limb?
Saphenous n.
No motor innervation - cutaneous sensory only
What is a autonomous zone?
Area supplied by only 1 cutaneous nerve
What is an overlap zone?
Area supplied by more than 1 cut. n.
Of the 2 zones of the cutaneous area, which ha the most diagnostic value? Why?
Autonomous zone
Indicates the damage/loss of innervation to one specific nerve
What are the differences in a cutaneous area and a dermatome?
Cutaneous area - supplied by a specific cutaneous n. Dermatomes - only specifies the area served by a spinal nerve.
What is found in muscle nerves and not in cutaneous nerves?
somatic efferents
where can muscle nerves originate from? (which primary branches?)
Dorsal and ventral primary branches
What is Sweeny?
muscle atrophy in horse due to damage to the suprascapular nerve.
Sensory innervation still intact for that area
What are 2 examples of mixed nerves?
Where do they have sensory functions in relation to the limb?
Radial and femoral nerves
distal limbs
What type of ganglionic fiber has myelinated fibers, cell bodies in the CNS, and terminate in the periphery?
preganglionic fiber
What type of ganglionic fiber has unmyelinated fibers, cell bodies in the periphery, and terminate in either the paravertebral, prevertebral, or terminal ganglia regions?
postganglionic fiber
sympathetic nerves have ______ preganglions and ______post ganglions.
short
long
parasympathetic neves have _______preGs and _______postGs.
long
short
Where do nerves come out from in parasympathetics?
craniosacral division
What is another name for the sympathetic division of the ANS?
the thoracosacral division
Where are the chain ganglia in paraSyms?
Haha Nope. You have no chain ganglia here!
Where do postG ParaSym fibers go?
cardiac muscle, glands, smooth muscle of eye, GIT, resp, and urogenital systems.
Where do postG Sym fibers go?
- cardiac muscle, all glands, and all smooth muscles of body
- run in ALL spinal nerves and most of cranial nerves to their peripheral branches
What fiber type are these characteristics:
“Anabolic Type”
operates locally
“Rest and Digest”
parasympathetic
What fiber type has these characteristics:
“catabolic type”
operates globally
“Fight or flight”
sympathetic
Cholinergic parasym postG fibers released what neurotransmitter?
acetylcholine
Adrenergic sym postG fibers release what neurotransmitter?
norepiniphrine
acetylcholine is from what type of fibers?
parasym postG fibers
norepinephrine is from what type of fibers?
sym postG fibers
What are the 2 receptors for acetylcholine?
nicotinic and muscarinic
Where are nicotinic receptors found? what do they respond to?
- pre/postG junctions of both sym and parasym systems
- all somatic neuromuscular junctions (between somatic efferents and skeletal muscle)
- respond to acetylcholine
Where are muscarinic receptors found and what do they respond to?
- parasym postG effector junction
- acetycholine
Where are adrenergic receptors found and what do they respond to?
- sym postG effector junctions
- norepinephrine
What is the route of sym nerve fibers to the head/C1/C2 region?
- exit T1
- pass through cervicothoracic ganglion to travel in sympathetic trunk
- synapse in cranial cervical ganglion
- postG from fibers from C1/C2 go back vua communicating branches
- postG for head travel via plexus around internal carotid
What does damage to the vagosympathetic trunk do?
- HORNERS!!!!!
- eliminates preG to cranial cervical ganglion
- **sympathetic supply to head removed!!!!!
What is the route of sym nerve fibers to the abdominal/pelvuc cavities and the genitalia?
- from T8-L3
- enter sympathetic trunk
- leave either via splanchnic n. or L1-L4 lumbar splanchnic n.
- synapse in prevertebral ganglia
- travel to effector organ via arterial plexuses
- preGs for pelvis/urogenitals synapse in caudal mesenteric G and postG leave from hypogastric n. to pass through pelviv plexus
- PreG to genitals synapse in pelvic plexus or sacral chain G
What do the sympathetics do to innervate the body wall? Where do they go and how do they get back?
- from L1-Cd lat horn to sym trunkto synapse in chain G
- back: communicating branch to body wall
What is the parasym route for fibers to visceral organs to the transverse colon?
- vagus n. >vagosym trunk>dorsal/ventral vagal trunks>abdominal autonomic plexuses (don’t synapse)>terminal G (synapse) in effector organ
- short postGs run from terminal G to effector
What is the parasym route for fiber to visceral orgasn distal to transverse colon?
-S1-S2>PELVIC N.>pelvic plexus (most synapse here)>others fibers may cont and synapse in terminal G