Spermatogenisis And Sperm Maturation Flashcards
Spermatogenesis
Spermatozoa are produced in the testis
What do testsis produce
Hormones and spermatozoa
What is the tunica albuginea?
White fibrous capsule
septa divide the organ into compartments containing
seminiferous tubules where sperm are produced and meiosis occurs
Leydig cells
clusters of cells between the seminiferous tubules and source of testosterone
Sertoli cells promote sperm cell development
blood-testis barrier is formed by tight junctions between
sertoli cells; separating sperm from immune system
Seminiferous tubules drain into network called rete testis
Why is thermoregulation of testis necessary?
As sperm are not produced at core body temperature
Heat exchange of pampinfiomr plexus
Spermatogenisis produces 2 types of daughter cells
- type A spermatagoonia remain outside blood-testis barrier & produce more
daughter cells until death
– type B differentiate into primary spermatocytes-Type B is still diploid
• cells must pass through Blood testis barrier to move inward toward lumen - new tight junctions form behind these cells
• meiosis I leads to 2 secondary spermatocytes
• meiosis II leads to 4 spermatids
How are spermatids transformed to spermatozoa?
Through the process of spermoiogenisis
sprouts tail and discards cytoplasm to become lighter
Process of spermatogenesis produces
300 to 600 sperm are made per gram of testis per second
-50g x 50 min x 60 sec x 500 sperm = 75,000,000 spermatozoa
Sertoli cells are important in spermatogenisis
Blood-testis barrier is formed by tight junctions between and basement membrane under sertoli cells.
Efferent ductules
12 small ciliated ducts collecting sperm from the rete testes and transporting it to the epididymis
Epididymis (head body and tail)
site of sperm maturation & storage (fertile for 40 to 60 days)
Ductus vas deferens
– musculartube45cmlongpassingup from scrotum through inguinal canal to posterior surface of bladder
– widens into a terminal ampulla
Ejaculatory duct
– 2 cm duct formed from ductus deferens & seminal vesicle & passing through prostate to empty into urethra