Spectrum of Commonly used Agents Flashcards
Amoxicillin and Ampicillin have a good ……….. absorption?
oral
Flucloxacillin is resistant to to the actions of ……………. and this makes it a good choice of treatment for Staphylococcal infections.
Staphylococcal B-lactamase
Piperacillin is a broad spectrum penicillin with extended what cover?
Gram negative cover
Piperacillin is useful against Enterococcus faecalis and is also active against what?
Pseudomonas species
What is Tazocin?
A combination of piperacillin and B-lactamase inhibitor tazobactam
Imipenem and meropenem belong to what sub group?
the carbapenems
Cephalosporins activity against gram negative organisms follows what pattern?
activity increase from first generation drugs through to second and to third.
Cephalosporins activity against gram positive organisms follows what pattern?
activity decrease proportionately from first generation through to third generation drugs.
Quinolones are active against what type of bacteria?
Almost all gram negative organisms including Pseudomonas.
In the treatment of Psueudomonas can be treated with?
Quinolones
Metronidazole is effective against what type of bacteria
anaerobes both gram negative and positive
what is fusidic acid used for?
as an anti staphylococcal drug
what should fusidic acid be used with
other anti staphycoccal drugs such as flucloxacillin
What can Trimethoprim be used alone for
UTI
Tetracyclines are broad spectrum agents which inhibit what?
bacterial protein synthesis
Clindamycin has good activity against what?
gram positive organisms and anaerobes
what is an advantage of Clindamycin?
it has very good tissue penetrationand can be takken oraly
Nalidixic acid is a urinary antiseptic, can be used against what?
activity only against gram negative aerobes
Nitrofurantoin is a urinary antiseptic with activity against what ?
most gram negative organisms except pseudomonas , also some gram positive organisms
