Spectrum of Commonly used Agents Flashcards

1
Q

Amoxicillin and Ampicillin have a good ……….. absorption?

A

oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Flucloxacillin is resistant to to the actions of ……………. and this makes it a good choice of treatment for Staphylococcal infections.

A

Staphylococcal B-lactamase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Piperacillin is a broad spectrum penicillin with extended what cover?

A

Gram negative cover

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Piperacillin is useful against Enterococcus faecalis and is also active against what?

A

Pseudomonas species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is Tazocin?

A

A combination of piperacillin and B-lactamase inhibitor tazobactam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Imipenem and meropenem belong to what sub group?

A

the carbapenems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cephalosporins activity against gram negative organisms follows what pattern?

A

activity increase from first generation drugs through to second and to third.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cephalosporins activity against gram positive organisms follows what pattern?

A

activity decrease proportionately from first generation through to third generation drugs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Quinolones are active against what type of bacteria?

A

Almost all gram negative organisms including Pseudomonas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In the treatment of Psueudomonas can be treated with?

A

Quinolones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Metronidazole is effective against what type of bacteria

A

anaerobes both gram negative and positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is fusidic acid used for?

A

as an anti staphylococcal drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what should fusidic acid be used with

A

other anti staphycoccal drugs such as flucloxacillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What can Trimethoprim be used alone for

A

UTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tetracyclines are broad spectrum agents which inhibit what?

A

bacterial protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Clindamycin has good activity against what?

A

gram positive organisms and anaerobes

17
Q

what is an advantage of Clindamycin?

A

it has very good tissue penetrationand can be takken oraly

18
Q

Nalidixic acid is a urinary antiseptic, can be used against what?

A

activity only against gram negative aerobes

19
Q

Nitrofurantoin is a urinary antiseptic with activity against what ?

A

most gram negative organisms except pseudomonas , also some gram positive organisms