Anti fungal drugs Flashcards
1
Q
What do polyenes bind to?
A
ergosterol present in the fungal cell wall
2
Q
what are polyenes active against?
A
Yeasts and filamentous fungi
3
Q
What is Amphotericin B?
A
polyene drug that is available for IV use
4
Q
What is a possible problem with the use of Amphotericin B
A
It is toxic
5
Q
What is the polyene drug that is available for topical use only?
A
Nystatin
6
Q
What do the Azoles do?
A
they inhibit ergosterol sythesis
7
Q
What is fluconazole used to treat?
A
yeast infections
8
Q
What are Voriconazole used to treat?
A
aspergillosis
9
Q
What do Allyamines do?
A
inhibit ergosterol synthesis
10
Q
name a allyamine
A
terbinafine
11
Q
what is the allyamine terbinafine used for?
A
fungal infection of the skin and nails
