Spectrum of Activity

Question 1

Activity against Pseudomonas

Answer 1

Piperacillin/tazobactam
Ceftazidime, Ceftazidime/avibactam
Cefepime
Ceftolozane/tazobactam
Imipenem/cilistatin, Doripenem, Meropenem
Aztreonam
Fosfomycin (urine only)
Ciprofloxacin, levofloxacin, delafloxacin
Gentamicin, Tobramycin, amikacin, Plazomicin
Colistimethate, polymyxin B

Question 2

Activity against Anaerobes

Answer 2

Amoxicillin/clavulanate 
Ampicillin/sulbactam
Piperacillin/tazobactam
Imipenem/cilistatin
Doripenem, Meropenem, Ertapenem
Clindamycin
Metronidazole, Secnidazole
Moxifloxacin, Delafloxacin
Tigecycline, Omadacycline, Eravacycline

Question 3

Activity against MRSA

Answer 3

Ceftaroline
Vancomycin; Telavancin, Dalbavancin, Oritavancin
Daptomycin
Linezolid, Tedizolid
Quinupristin/dalfopristin
Sulfamethoxazole/trimethoprim
Clindamycin (empiric tx)
Fosfomycin (urine only)
Rifampin, Rifabutin (empiric tx)
Doxycycline, Minocycline (CA-MRSA)
Tigecycline, Omadacycline, Eravacycline
Delafloxacin; Ozenoxacin cream

Question 4

Activity against Atypicals

Answer 4

Fluoroquinolones: Moxifloxacin, Gemifloxacin, Levofloxacin, Ciprofloxacin, Delafloxacin, Ofloxacin, Ozenoxacin cream
Macrolides: Azithromycin, Clarithromycin, Erythromycin
Tetracyclines & derivatives: Tetracycline, Doxycycline, Minocycline; Tigecycline, Omadacycline, Eravacycline

Question 5

Gram Positive activity ONLY

Answer 5

Vancomycin, Telavancin, Dalbavancin, Oritavancin
Daptomycin
Linezolid, Tedizolid
Quinupristin/dalfopristin
Nafcillin, Oxacillin, Dicloxacillin

Question 6

Gram Negative Coverage ONLY

Answer 6

Aztreonam
Rifaxamin
Colistimethate (Colistin)

Question 7

C. difficile treatment

Answer 7

Vancomycin - PO only
Fidaximicin
Metronidazole