ID Chapter Flashcards
Liquid ABX that require refrigeration after reconstitution
Penicillin VK, Ampicillin, Amox/Clavulanate
Cephalexin, cefadroxil, cefpodoxime, cefprozil, cefuroxime, cefaclor, ceftibuten
Vacomycin (Firvanq)
Valganciclolovir (Valcyte)
Refrigeration Recommended
Amoxicillin - improves taste
Do NOT refrigerate - PO
Cefdinir (Omnicef)
Azithromycin
Clarithromycin (Biaxin) - bitter taste, thickens, gels
Doxycycline (Vibramycin)
Ciprofloxacin (Cleocin), levofloxacin (Levaquin)
Clindamycin (Cleocin) - thickens, may crystallize
Linezolid (Zyvox)
Sulfamethoxazole/Trimethoprim (Sulfatrim)
Acyclovir (Zovirax)
Fluconazole (Diflucan)
Posaconazole (Noxafil)
Voriconazole (Vfend)
Nystatin
Do NOT refrigerate - IV
Metronidazole (Flagyl)
Moxifloxacin (Avelox)
Sulfamethoxazole/Trimethoprim (Sulfatrim)
Acyclovir (Zovirax) - refrigeration causes crystalation
No Renal Dose Adjustments Required
Antistaphylococcal PCNs: dicloxacillin, nafcillin, oxacillin Ceftriaxone Clindamycin Doxycycline Macrolides: Azithromycin & Erythromycin only Metronidazole Moxifloxacin Linezolid (others listed on pg. 370 of RxPrep)
1:1 IV to PO
Levofloxacin, Moxifloxacin Doxycycline, Minocycline Sulfamethoxazole/Trimethoprim Linezolid, Tedizolid Metronidazole Fluconazole, Isavuconazonium, Posaconazole (PO tabs & IV), Voriconazole
Abx to take with food
Ampicillin caps & suspension Penicillin VK Ceftibuten suspension Levofloxacin suspension Rifampin, Isoniazid, Itraconazole soln, Voriconazole
Protect from Light during Administration
Doxycycline
Micafungin
Pentamidine
IV meds compatible with Dextrose ONLY
Dalbavancin, Oritavancin Pentamidine Quinupristine/Dalfopristin Sulfamethoxazole/Trimethoprim Amphotericin B (conventional, Abelcet, Ambisome)
IV meds compatible with saline ONLY
Ampicillin
Ampicillin/Sulbactam
Ertapenem
Daptomycin (Cubicin RF - specific reconstitution requirements)
IV meds contabile with NS/LR ONLY
Daptomycin (Cubicin)
Caspofungin
Drugs of choice for CA-MRSA infections (RxPrep)
SMX/TMP
Doxycycline, minocycline
Clindamycin
Linezolid
Drugs of choice for Nosocomial MRSA infections (RxPrep)
Vancomycin (consider alternate if MIC >= 2)
Linezolid
Daptomycin (not pneumonia)
Rifampin (select infections but never used alone)
Telavancin
Drugs of choice for More severe SSTIs requiring IV treatment or hospitalization (covers MRSA and Streptococci) (RxPrep)
Vancomycin (consider alternate if MIC >= 2) Linezolid, tedizolid Daptomycin Ceftaroline Telavancin, oritavancin, dalbavancin Quinupristin/Dalfopristin Tigecycline
Drugs of choice for VRE (E. faecalis) (RxPrep)
Pen G or ampicillin Linezolid Daptomycin Tigecycline Cystitis only: nitrofurantoin, fosfomycin, doxycycline
Drugs of choice for VRE (E. faecium) (RxPrep)
Daptomycin Linezolid Quinupristin/Dalfopristin Tigecycline Cystitis only: nitrofurantoin, fosfomycin, doxycycline
Drugs of choice for Pseudomonas aeruginosa (RxPrep)
Piperacillin/Tazobactam Cefepime Ceftazidime Ceftazidime/Avibactam Ceftolozane/Tazobactam Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam) Ciprofloxacin, levofloxacin Aztreonam Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin) Colistimethate, polymixin B
Drugs of choice for Acinetobacter baumannii (RxPrep)
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam) Ampicillin/sulbactam Minocycline Tigecycline Quinolones SMX/TMP Colistimethate, polymyxin B
Drugs of choice Extended Spectrum Beta-lactamase producing Gram-Negative rods (ESBL GNR) - E. coli, K. pneumonia, P. mirabilis for (RxPrep)
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam, ertapenem)
Ceftolozane/Tazobactam
Ceftazidime/Avibactam
Cefepime (high-dose)
Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin)
Cystitis only: Fosfomycin
Drugs of choice Carbapenem-resistant Gram-negative rods (CRE) for (RxPrep)
Ceftazidime/Avibactam
Colistimethate, polymyxin B
Drugs of choice for Bacteroides fragilis (RxPrep)
Metronidazole
Beta-lactam/beta-lactamase inhibitor (amox/clavulanate, ampicillin/sulbactam)
Cefotetan, cefoxitin
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, ertapenem)
Tigecycline
Others (reduced activity): Clindamycin, moxifloxacin
Drugs of choice for C. difficile infection (RxPrep)
Vancomycin (PO)
Fidaxomicin
Metronidazole
Drugs of choice for Atypical Organisms (RxPrep)
Azithromycin, clarithromycin
Doxycycline, minocycline
Quinolones (enhanced coverage w/ gemifloxacin, levofloxacin, moxifloxacin)
Drugs of choice for HNPEK (Haemophilus influenzae, Neisseria spp., Proteus mirabilis, E. coli, Klebsiella spp) infections (RxPrep)
Beta-lactam/beta-lactamase inhibitor (Amox/clavulanate, ampicillin/sulbactam)
Amoxicillin (if beta-lactamase negative)
Cephalosporins (not 1st generation; cefuroxime, cefotetan, cefoxitin, cefotaxime, ceftriaxone, ceftazidime, ceftazidime/avibactam, ceftolozane/tazobactam, ceftaroline)
Carbapenems (doripenem, imipenem/cilastatin, meropenem, ertapenem)
SMX/TMP
Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin)
Quinolones
