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NAPLEX Review > ID Chapter > Flashcards

ID Chapter Flashcards

1
Q

Liquid ABX that require refrigeration after reconstitution

A

Penicillin VK, Ampicillin, Amox/Clavulanate
Cephalexin, cefadroxil, cefpodoxime, cefprozil, cefuroxime, cefaclor, ceftibuten
Vacomycin (Firvanq)
Valganciclolovir (Valcyte)

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2
Q

Refrigeration Recommended

A

Amoxicillin - improves taste

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3
Q

Do NOT refrigerate - PO

A

Cefdinir (Omnicef)
Azithromycin
Clarithromycin (Biaxin) - bitter taste, thickens, gels
Doxycycline (Vibramycin)
Ciprofloxacin (Cleocin), levofloxacin (Levaquin)
Clindamycin (Cleocin) - thickens, may crystallize
Linezolid (Zyvox)
Sulfamethoxazole/Trimethoprim (Sulfatrim)
Acyclovir (Zovirax)
Fluconazole (Diflucan)
Posaconazole (Noxafil)
Voriconazole (Vfend)
Nystatin

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4
Q

Do NOT refrigerate - IV

A

Metronidazole (Flagyl)
Moxifloxacin (Avelox)
Sulfamethoxazole/Trimethoprim (Sulfatrim)
Acyclovir (Zovirax) - refrigeration causes crystalation

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5
Q

No Renal Dose Adjustments Required

A 
Antistaphylococcal PCNs: dicloxacillin, nafcillin, oxacillin
Ceftriaxone
Clindamycin
Doxycycline
Macrolides: Azithromycin & Erythromycin only
Metronidazole
Moxifloxacin
Linezolid
(others listed on pg. 370 of RxPrep)
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6
Q

1:1 IV to PO

A 
Levofloxacin, Moxifloxacin
Doxycycline, Minocycline
Sulfamethoxazole/Trimethoprim
Linezolid, Tedizolid
Metronidazole
Fluconazole, Isavuconazonium, Posaconazole (PO tabs & IV), Voriconazole
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7
Q

Abx to take with food

A 
Ampicillin caps & suspension
Penicillin VK
Ceftibuten suspension
Levofloxacin suspension
Rifampin, Isoniazid, Itraconazole soln, Voriconazole
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8
Q

Protect from Light during Administration

A

Doxycycline
Micafungin
Pentamidine

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9
Q

IV meds compatible with Dextrose ONLY

A 
Dalbavancin, Oritavancin
Pentamidine
Quinupristine/Dalfopristin
Sulfamethoxazole/Trimethoprim
Amphotericin B (conventional, Abelcet, Ambisome)
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10
Q

IV meds compatible with saline ONLY

A

Ampicillin
Ampicillin/Sulbactam
Ertapenem
Daptomycin (Cubicin RF - specific reconstitution requirements)

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11
Q

IV meds contabile with NS/LR ONLY

A

Daptomycin (Cubicin)

Caspofungin

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12
Q

Drugs of choice for CA-MRSA infections (RxPrep)

A

SMX/TMP
Doxycycline, minocycline
Clindamycin
Linezolid

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13
Q

Drugs of choice for Nosocomial MRSA infections (RxPrep)

A

Vancomycin (consider alternate if MIC >= 2)
Linezolid
Daptomycin (not pneumonia)
Rifampin (select infections but never used alone)
Telavancin

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14
Q

Drugs of choice for More severe SSTIs requiring IV treatment or hospitalization (covers MRSA and Streptococci) (RxPrep)

A 
Vancomycin (consider alternate if MIC >= 2)
Linezolid, tedizolid
Daptomycin
Ceftaroline
Telavancin, oritavancin, dalbavancin
Quinupristin/Dalfopristin
Tigecycline
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15
Q

Drugs of choice for VRE (E. faecalis) (RxPrep)

A 
Pen G or ampicillin
Linezolid
Daptomycin
Tigecycline
Cystitis only: nitrofurantoin, fosfomycin, doxycycline
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16
Q

Drugs of choice for VRE (E. faecium) (RxPrep)

A 
Daptomycin
Linezolid
Quinupristin/Dalfopristin
Tigecycline
Cystitis only: nitrofurantoin, fosfomycin, doxycycline
17
Q

Drugs of choice for Pseudomonas aeruginosa (RxPrep)

A 
Piperacillin/Tazobactam
Cefepime
Ceftazidime
Ceftazidime/Avibactam
Ceftolozane/Tazobactam
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam)
Ciprofloxacin, levofloxacin
Aztreonam
Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin)
Colistimethate, polymixin B
18
Q

Drugs of choice for Acinetobacter baumannii (RxPrep)

A 
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam)
Ampicillin/sulbactam
Minocycline
Tigecycline
Quinolones
SMX/TMP
Colistimethate, polymyxin B
19
Q

Drugs of choice Extended Spectrum Beta-lactamase producing Gram-Negative rods (ESBL GNR) - E. coli, K. pneumonia, P. mirabilis for (RxPrep)

A

Carbapenems (doripenem, imipenem/cilastatin, Meropenem, meropenem/vaborbactam, ertapenem)
Ceftolozane/Tazobactam
Ceftazidime/Avibactam
Cefepime (high-dose)
Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin)
Cystitis only: Fosfomycin

20
Q

Drugs of choice Carbapenem-resistant Gram-negative rods (CRE) for (RxPrep)

A

Ceftazidime/Avibactam

Colistimethate, polymyxin B

21
Q

Drugs of choice for Bacteroides fragilis (RxPrep)

A

Metronidazole
Beta-lactam/beta-lactamase inhibitor (amox/clavulanate, ampicillin/sulbactam)
Cefotetan, cefoxitin
Carbapenems (doripenem, imipenem/cilastatin, Meropenem, ertapenem)
Tigecycline
Others (reduced activity): Clindamycin, moxifloxacin

22
Q

Drugs of choice for C. difficile infection (RxPrep)

A

Vancomycin (PO)
Fidaxomicin
Metronidazole

23
Q

Drugs of choice for Atypical Organisms (RxPrep)

A

Azithromycin, clarithromycin
Doxycycline, minocycline
Quinolones (enhanced coverage w/ gemifloxacin, levofloxacin, moxifloxacin)

24
Q

Drugs of choice for HNPEK (Haemophilus influenzae, Neisseria spp., Proteus mirabilis, E. coli, Klebsiella spp) infections (RxPrep)

A

Beta-lactam/beta-lactamase inhibitor (Amox/clavulanate, ampicillin/sulbactam)
Amoxicillin (if beta-lactamase negative)
Cephalosporins (not 1st generation; cefuroxime, cefotetan, cefoxitin, cefotaxime, ceftriaxone, ceftazidime, ceftazidime/avibactam, ceftolozane/tazobactam, ceftaroline)
Carbapenems (doripenem, imipenem/cilastatin, meropenem, ertapenem)
SMX/TMP
Aminoglycosides (gentamicin, tobramycin, amikacin, streptomycin, Plazomicin)
Quinolones

NAPLEX Review (4 decks)

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