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Biochem > Specificity rules for endopeptidases > Flashcards

Specificity rules for endopeptidases Flashcards

1
Q

Trypsin

A

Cleaves positively charged residues
- Lys
- Arg
Wont cleave proline

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2
Q

Chymotrypsin

A

Cleaves bulky hydrophobic residues
- Phe
- Trp
- Tyr
Wont cleave proline

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3
Q

Elastase

A

Small neutral residues
- Ala
- Gly
- Ser
- Val
Will not cleave proline

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4
Q

Thermolysin

A
  • Ile
  • Met
  • Phe
  • Trp
  • Tyr
  • Val
    Will not cleave proline
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5
Q

Pepsin

A
  • Leu
  • Phe
  • Trp
  • Tyr
    Will not cleave proline
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6
Q

Endopeptidase V8

A
  • Glu
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Biochem (22 decks)

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