Specific pathogen groups Flashcards
Legionella name
Legionella pneumophilia
Legionella gram
Negative rod
Aerobic
Where does legionella live?
Soil, warm water, moist areas
Chlorine tolerant.
Legionella transmission
Usually inhalataion but you can get it from swimming in water.
No human to human.
Legionairre’s disease
atypical lobal pneumonia
1-5% of CAP
incubation 2-10 days
Legionairre’s fatality
30%
Legionairre’s symptoms.
Fever, malaise, myalgia, anorexia, headache, cough, chest pain,system involvement.
Legionairre’s systemic symptoms
GI- diarrhoea, pancreatitis, peritonitis
Neuro- headache, enceph
Heart- myocarditis, pericarditis, endo
Acute renal failure.
Pontiac fever
90% of legionella
Flu like symptoms
Recovers in 1 week
No treatment.
Diagnosis legionella
sputum culture 3-5 days
Urinary sample= hours
serology 4-8 weeks
Treatment legionella
Clarithromycin +- rifampicin
Doxy
Notify public health.
Pseudomonas source
water, soil, plant, animals, hot tubs, moist environments
hospital disinfectants, food, sink, showers, mops etc
Pseudomonas transmission
human to human
human to source
ingestion of food/water
opportunistic from nosocomial.
Pseudomonas structure
have pili to attach to host
capsulated
cytotoxins and proteases locally invade and disseminate.
Pseudomonas presentation
severe HAP immunocompromised
eye- keratitis, ear- otitis externa, skin, hot tub folliculitis, surgical wounds, bone- osteomyelitis, septic arthritis, CNS- meningitis, brain abscess, UTI, Pneumonia- COPD, CCF, CF, ventilated
