Specific Cell Functions

Question 1

What are the functions of the outer membrane of the mitochondria?

Answer 1

• Fatty acid elongation and desaturation
• Phospholipid synthesis
• Monoamine oxidase

Question 2

What are the functions of the inner membrane of the mitochondria?

Answer 2

• ETC
• Oxidative phosphorylation
• Transhydrogenase
• Transport systems
• Fatty acid transport

Question 3

What are the functions of the matrix of the mitochondria?

Answer 3

• PDH complex
• TCA
• Glutamate DH
• Fatty acid DH
• Urea cycle
• Replication/Transcription/Translation

Question 4

This drug is used to treat gout.

Answer 4

Colchicine

Question 5

These two drugs are used in the treatment of cancers and have a high mitotic index (bind to tubulin and prevent polymerization).

Answer 5

Vincristine, Vinblastine

Question 6

This drug binds and stabilizes microtubules (inhibiting depolymerization), specifically blocking mitosis. Used in the treatment of cancers.

Answer 6

Paclitaxel (Taxol)

Question 7

These two drugs block F-actin depolymerization.

Answer 7

• Cytochalasins (excreted by fungi)

- Phalloidin (toadstool mushroom)

Question 8

This drug binds free G-actin monomers, so it inhibits polymerization (or the synthesis of F-actin).

Answer 8

Lactrunculin (extracted from sea sponge)