Specific antidotes Flashcards

p 239 (complete)

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

Salicylates (2)

A

NaHCO3 (alkalinize urine); dialysis

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3
Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

Acetylcholinesterase inhibitors, organophosphates (2)

A

Atropine–>pralidoxime

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5
Q

Antimuscarinic, anticholinergic agents (2)

A

Physostigmine; control hyperthermia

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6
Q

Beta-blockers

A

Glucagon

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7
Q

Digitalis (3)

A

Normalize K; Anti-dig Fab fragments; Mg

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8
Q

Iron (2)

A

Deferoxamine; deferasirox

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9
Q

Lead (4)

A

CaEDTA; dimercaprol; succimer; penicillamine

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10
Q

Mercury (2)

A

Dimercaprol (BAL); succimer

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11
Q

Copper

A

Penicillamine

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12
Q

Cyanide (2 options)

A

Nitrite + thiosulfate; hydroxocobalamin

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13
Q

Methemoglobin (2)

A

Methylene blue; vitamin C

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14
Q

Carbon monoxide

A

100% O2 or hyperbaric O2

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15
Q

Methanol; ethylene glycol (3)

A

Fomepizole > ethanol, dialysis

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16
Q

Opioids

A

Naloxone

17
Q

Benzodiazepines

A

Flumazenil

18
Q

TCAs

A

NaHCO3 (plasma alkalinization)

19
Q

Heparin

A

Protamine sulfate

20
Q

Warfarin

A

Vitamin K; FFP (if actively bleeding)

21
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

22
Q

Theophylline

A

Beta-blocker

23
Q

Arsenic (3)

A

Penicillamine, dimercaprol, succimer

24
Q

Gold (3)

A

Penicillamine, dimercaprol, succimer