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First Aid: General Pharm > Drug AEs and DDIs > Flashcards

Drug AEs and DDIs Flashcards

P240-242 (complete)

1
Q

Coronary vasospasm

A

Cocaine
Sumatriptan
Ergot alkaloids

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2
Q

Cutaneous flushing

A 
Vancomycin
Adenosine
Niacin
Ca channel blockers
(mnemonic=VANC)
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3
Q

Dilated cardiomyopathy

A

Anthracyclines (esp doxorubicin & daunorubicin)

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4
Q

Torsades de pointes

A

Class III (sotalol) and class IA (quinidine) antiarrhythmics

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5
Q

Agranulocytosis

A 
Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone
(mnemonic=Agranulocytosis Could Certainly Cause Pretty Major Damage)
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6
Q

Aplastic anemia

A 
Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole
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7
Q

Direct Coombs positive anemia

A

Methyldopa

Penicillin

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8
Q

Gray baby syndrome

A

Chloramphenicol

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9
Q

Gray-blue people (smurfs!)

A

Amiodarone

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10
Q

Hemolysis in G6PDH-deficient patients

A 
Isoniazid (INH)
Sulfonamides
Primaquine
Aspirin
Ibuprofin
Nitrofurantoin
(mnemonic=Hemolysis IS PAIN)
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11
Q

Megaloblastic anemia

A

Phenytoin
Methotrexate
Sulfa drugs (mnemonic=Having a blast with PMS)

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12
Q

Thrombotic complications

A

OCPs (ex: estrogen)

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13
Q

Cough

A

ACE inhibitors (main reason for change to ARBs)

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14
Q

Pulmonary fibrosis

A

Bleomycin
Amiodarone
Busulfan
(mnemonic=It’s hard to BLAB when you have plum fibrosis)

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15
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

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16
Q

Focal to massive hepatic necrosis

A 
Halothane
Amanita phalloides
Valproic acid
Acetaminophen
(mnemonic=Liver "HAVAc)
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17
Q

Hepatitis

A

INH

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18
Q

Pseudomembranous colitis

A

Clindamycin

Ampicillin

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19
Q

Adrenocortical insufficiency

A

Glucocorticoid withdrawal (HPA suppression)

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20
Q

Gynecomastia

A 
Spironolactone
Digitalis
Cimetidine
chronic Alcohol use
Estrogens
Ketoconazole
(mnemonic=Some Drugs Create Awkward Knockers)
21
Q

Hot flashes

A

Tamoxifen

Clomiphene

22
Q

Hyperglycemia

A 
Niacin
Tacrolimus
Protease inhibitors
HCTZ
Corticosteroids
23
Q

Hypothyroidism

A

Lithium
Amiodarone
Sulfonamides

24
Q

Fat redistribution

A

Glucocorticoids

Protease inhibitors

25
Q

Gingival hyperplasia

A

Phenytoin

Verapamil

26
Q

Gout

A

Furosemide
Thiazides
Niacin
Cyclosporine

27
Q

Myopathies

A 
Fibrates
Niacin
Colchicine
Hydroxychloroquine
IFN-alpha
Penicillamine
Statins
Glococorticoids
(mnemonic=Fish N CHIPS Give you myopathies)
28
Q

Osteoporosis

A

Corticosteroids

Heparin

29
Q

Photosensitivity

A

Sulfonamides
Amiodarone
Tetracycline
(SAT for a photo)

30
Q

Rash (stevens-johnson syndrome)

A 
Penicillin
Ethosuximide
Carbamazepine
Sulfa drugs
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital
(Bad rash after a PEC SLAPP)
31
Q

SLE-like syndrome

A 
Hydralazine
INH
Procainamide 
Phenytoin
(It's not HIPP to have lupus)
32
Q

Teeth (kids)

A

Tetracyclines

33
Q

Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

34
Q

Diabetes insipidus

A

Lithium

Demeclocycline

35
Q

Fanconi’s syndrome

A

Expired tetracycline

36
Q

Hemorrhagic cystitis

A

Cyclophosphamide
Ifosamide
(prevent by giving w/ Mesna)

37
Q

Interstitial nephritis

A

Methicillin
NSAIDs
Furosemide

38
Q

SIADH

A

Carbamazepine

Cyclophosphamide

39
Q

Cinchonism

A

Quinidine

Quinine

40
Q

Parkinson-like syndrome

A

Antipsychotics
Reserpine
Metoclopramide

41
Q

Seizures

A 
Isoniazid
Bupropion
Imipenem/cilastatin
Tramadol
Enflurane
Metoclopramine
(with seizures, I BITE My tongue)
42
Q

Tardive dyskinesia

A

Antipsychotics

43
Q

Antimuscarinic

A

Atropine
TCAs
H1-blockers
Neuroleptics

44
Q

Disulfiram-like rxn

A

Metronidazole
Some cephalosporins
Procarbazine
1st gen sulfonylureas

45
Q

Nephrotoxicity/ototoxicity

A

Aminoglycosides
Vancomycin
Loop diuretics
Cisplatin

46
Q

P450 Inducers

A 
Modafinil
Barbiturates
St. John's wort
Phenytoin
Rifampin
Griseofulvin
Carbamazepine
Chronic alcohol use
(Momma Barb Steals Phen-phen and Refuses Greasy Carbs ChronicAlly)
47
Q

P450 inhibitors

A 
Macrolides
Amiodarone
Grapefruit juice
Isoniazid
Cimetidine
Ritonavir
Acute alcohol abuse
Ciprofloxacin
Ketoconazole
Sulfonamides
Gemfibrozil
Quinidine
(MAGIC RACKS in GQ)
48
Q

List the sulfa drugs

A 
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide antibiotics
Sulfasalazine
Sulfonylureas
(Popular FACTSSS)
49
Q

AEs with sulfa drugs?

A 
Fever
UTI
Pruritic rash
SJS
Hemolytic anemia
Thrombocytopenia
Agranulocytosis
Urticaria
Symptoms range from mild to life-threatening

First Aid: General Pharm (2 decks)

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