Specialty Disciplines -- Fortie, Michaud, Sherrill, and Hayes Flashcards
If you have autonomous overproduction of hormones, how will this affect trophic hormone levels?
Trophic hormone levels will decrease
Immature face, infantile voice, sparse/thin hair growth, delayed puberty should make you think of?
Growth hormone deficiency
What component of the physical exam is very important in evaluating growth hormone deficiency?
Neuro – make sure there isn’t a tumor causing the symptoms
How do we diagnose growth hormone deficiency?
Provocative testing – give insulin which should stimulate growth hormone release. Helps determine where the growth hormone issue is.
How do we treat growth hormone deficiency?
Give growth hormone exogenously – sub q injections
When giving glucose, what should happen to growth hormone levels?
Decrease
How do we treat excessive growth hormone?
Somatostatin or if tumor, resect
___________ will present with thick tongue, hypotonia, hypothermia, and bradycardia.
Hypothyroidism
What is the most common etiology of hypothyroidism/
Hashimoto’s
What medications can cause Hashimoto’s?
Amiodarone, lithium
What populations are more at risk for developing hypothyroidism?
Down syndrome and diabetics
Whats the difference between an acute and subacute thyroiditis?
Acute is typically a systemic infection. Thyroid is tender. Also presents with fever, chills, and sore throat.
Subacute is usually a viral presentation and thyroid isn’t as red and tender.
However – thyroiditis as a whole – think red and tender thyroid.
What mobilizes calcium from bone, increases renal absorption of calcium, and increases phosphate excretion?
Parathyroid hormone
What increases intestinal absorption of calcium?
Vitamin D
What increases bone deposition of calcium?
Calcitonin
Normal levels of this element are required for parathyroid gland function.
Magnesium.
Hypoparathyroidism is associated with hypo or hypercalcemia?
Hypocalcemia
How do we treat primary hypoparathyrodism?
Replace the calcium
People with Ricketts have the inability to absorb calcium — what must we replace so they can?
Vitamin D
What presents with polyuria, polydipsia, and acanthosis nigracans?
Type 1 DM
What is the first step in treating DKA?
Hydration to help correct the acidosis.
What is the SRY gene?
Sex determining gene on the Y chromosome
Autosomal recessive – deficiencies in the enzyme for production of cortisol.
What is this?
Congenital Adrenal Hyperplasia
How do we diagnose congenital adrenal hyperplasia?
cortisol and aldosterone level testing
may have elevated ACTH to stimulate more production
What is androgen insensitivity?
x-linked recessive
Can present in several different ways
Can be complete androgen insensitivity syndrome (CAIS) – born with normal appearing female genitalia
Partial androgen insensitivity syndrome (PAIS) – have testes that have not descended. Females will grow up and never get their period.
Mild androgen insensitivity syndrome (MAIS) – very few symptoms
This card sucks. Sorry.
If you see a patient with uveitis, what do you have to think of?
A rheumatological disorder
This type of arthritis will present with high intermittent fevers, a rash you can make pop up by rubbing the skin, and hepatosplenomegaly
Systemic Arthritis – or Stills Disease
This type of arthritis usually presents in younger children – starts in 1 or 2 joints, and then spreads to 5 joints within 6 months.
Polyarthritis
This type of arthritis presents similarly to polyarthritis, but typically even in younger ages (2-3), and has no additional joint involvement after 6 months.
Oligoarthritis
This type of arthritis is more typically associated with tendons – SI joint tenderness is a common complaint.
Enthesitis-related arthritis
This type of arthritis affects females more than males. DIP is often affected and may present with nail pitting.
Psoriatic arthritis
How do we treat rheumatological disorders? What is the progression?
- NSAIDs
- Corticosteroids
- Non-biologic DMARDs
- Biologic DMARDs
This is the most common vasculitis in children and presents with rash, palpable purpura, and small vessel inflammation
Henoch Scholien Purpura
This disease presents with a strawberry tongue and dry cracked mucosa. Often conjunctival hemorrhage as well.
Kawasaki disease
What do we have to worry about with Kawasaki disease?
Aneurysm formation
What presents with a malar rash, photosensitivity, raynaud’s, and mucosal sores?
Systemic Lupus Erythematous
How do we treat Lupus?
Corticosteroids, NSAIDs, Hydroxychloroquine (for skin issues)
What test is mandated by government to screen for a wide variety of metabolic disorders?
Tandem Mass Spectrometry
*This is the only thing I took away from that entire lecture
What are some signs of pediatric respiratory distress?
Tachycardia, retractions – intercostal and sternal, grunting, nasal flaring, head bobbing, abdominal breathing, tripod position
What presents with a “seal, barky” cough, “steeple sign” on x-ray, and inspiratory stridor?
Croup
What causes croup?
Parainfluenza virus
How do we treat croup?
Single dose of Decadron
Moderate to severe Croup: Racemic epi, oxygen, IV
This disease has a very rapid onset. Presents with drooling, stridor, and kids are often found sitting in tripod position
Epiglottitis
What vaccine has decreased incidence of epiglottitis?
HiB vaccine
What do you see on x-ray of someone with epiglottitis?
“thumb sign”
What must be your first line of treatment with someone suffering from epiglottitis?
Secure an airway
How do you diagnose influenza?
PCR nasal swab
What causes bronchiolitis?
RSV
What are signs and symptoms of RSV?
gradual onset o respiratory distress, fever, poor feeding, expiratory wheezing, and “junky” lung sounds
How do we diagnose RSV?
Nasal swab
How do we treat pertussis?
Macrolides (azithromycin)
What are the most common pathogens causing pneumonia?
Strep pneumoniae, H. flu, and mycoplasma
Fever and cough, rapid breathing/tachypnea, dyspnea, low oxygen saturation, lethargy, focal crackles, rales on auscultations are symptoms of?
Pneumonia
How do we treat pneumonia?
First Amoxicillin, then a macrolide – (in kids!)
What will a chest x-ray of pneumonia look like?
Consolidation, “round” appearing
Oxygen sat lower than 92%, RR greater than 70 in infants and > 50 in children, intermittent apnea or grunting, and dehydration are all reasons to?
Admit a child to the hospital
Abnormalities of salt and water transport across epithelial surfaces affecting the lungs and GI system describes?
Cystic Fibrosis
Greasy, foul-smelling stools and recurrent respiratory infections are symptoms of?
Cystic Fibrosis
How do we diagnose cystic fibrosis?
Positive sweat test
Chronic airway inflammatory disorder affecting mast cells, eosinophils, lymphocytes that cause inflammation leading to bronchospasm, bronchial edema, and increased mucus.
Asthma
How do we diagnose asthma?
PFT’s: if FEV/FVC improves by 12% with bronchodilator
How do we treat asthma?
Step-wise approach
I’ll leave it at that.
Room sharing, breastfeeding, pacifier during sleep, and placing infant on back to sleep are all?
Methods to reduce risk of SIDS
Few hours after birth baby goes into respiratory distress, you get an x-ray and it shows “ground-glass appearance”. Dx?
Hyaline Membrane Disease
How do we treat hyaline membrane disease?
Give surfactant
Kids stick things in places they shouldn’t. How do symptoms differ between an upper airway obstruction versus a lower airway obstruction?
Upper airway: stridor, choking, cough, cyanosis.
Complete obstruction – no cough or choking
Lower airway: unilateral wheezing, recurrent pneumonia, cough
Introduction of solid foods, toilet training, start of school, hypothyroid are all causes of?
Constipation
What might you find on PE of a kid with constipation?
Abdominal distension, palpable stool mass, soiled underwear, impacted stool on rectal exam
How do we treat constipation in infants?
Glycerin suppository, sorbitol-containing juices
How do we treat constipation in children?
Polyethylene glycol, disimpaction, diet change
How do we define diarrhea in peds?
Passage of loose or watery stools three or more times per day