Special Tissue Flashcards

1
Q

Stabilize the triple helix during alteration of body temperature

A

Hydroxyproline

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2
Q

Confer rigidity of collagen molecule

A

Proline

Hydroxyproline

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3
Q

Very third position most striking characteristics feature

A

Glycine

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4
Q

Anchoring fibrils

A

Type 7

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5
Q

Co factor of lysyl hydroxylase

A

Ascorbic acid

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6
Q

Pearl strings

A

Perlecan

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7
Q

Hexosamine unit of hyalunoric acid sulfate

A

Glucosaminoglycan

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8
Q

Inorganic component of the bone

A

Hydroxyapatite

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9
Q

Major proteoglycans in cartilage

A

Aggrecan

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10
Q

Osteoclastic activity > osteoblastic activity

A

Osteoporosis

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11
Q

5% of the semen is secreted by the

A

Littre gland

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12
Q

Elastin

A

Presence of hydroproline

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13
Q

Increase production of elastin

A

Scleroderma

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14
Q

An 18 year old man with curved femur and tibia fibula. She drink milk everyday.

A

Osteomalacia

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15
Q

Occasional alcoholic beverage presentable chronic pain at the joints, polarized with likely yellow

A

Blunt rod crystals

Rhombic shaped crystals

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16
Q

Cystic fibrosis

A

Sweat test

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17
Q

Marfan

A

Steinbergs test

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18
Q

Sever dryness of the eyes and tongue and tooth decay

A

Schirmers test

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19
Q

Dominance of fatty acids on the epidermal barrier

A

Psoriasis

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20
Q

Foreign body sensation and severe dryness of the eye

A

Sjorgen syndrome

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21
Q

A 2 year old child with recurring episodes of pneumonia and positive in sweat test

A

Cystic fibrosis

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22
Q

23 year old college student with coarse facial featyres, with corneal clouding. Deficient of arylsulfatase sulfase B.

A

Maroteaux Lamy

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23
Q

Low fibrilin levels, increased cytokine TGF

A

Marfan syndromw

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24
Q

Basement membrane

A

Collagen type 4

25
Q

Site of initial steps in the posttranslational modification of collagen

A

EDR

26
Q

Poor wound healing

A

Under hydroxylation

27
Q

True about elastin

A

Intramolecular desmosine cross links

28
Q

Roles of fibronectin

A

Cell adhesion
Cell differentiation
Cell migration

29
Q

Contains glucosaminoglycans

A

Heparin
Heparan
Hyalunoric acid

30
Q

Major cell attachment factor

A

Nidogen

31
Q

Defective collagen type 1

A

Osteogenesis imperfecta

32
Q

Low amounts of fibrin

A

Marfan syndrome

33
Q

Decrease to absence of elastin

A

Cutis laxa

34
Q

Excessive amount of elastin

A

Scleroderma

35
Q

Defect in lysyl oxidase

A

Menkes disease

36
Q

Only glycosaminoglycan does not undergo sulfation

A

Hyalunoric acid

37
Q

Clover leaf shape skull
Prominent eyes
Devlated toes. Defect in

A

FGFR1

38
Q

X linked mucopoyssachridose

A

Hunters syndrome

39
Q

Attachment of fibrolast to matrix

A

Laminin

40
Q

Negative charge of glycosaminoglycans

A

Sulfate

Carboxyl

41
Q

Charc of hyalunoric acid

A

Not sulfated
Not branched
Found in bacteria

42
Q

Most abundant type of glycosaminoglycan

A

Chondrotin sulfate

43
Q

Most common type of mucopolysaccharidosis

A

San filippo

44
Q

Inguinal and umbilical hernia

A

Hurler syndrom

45
Q

Mutation found in FBN2

A

Beals syndrome

46
Q

Hurler and hunter syndrome

A

Heparan and dermatan

47
Q

Schele syndrome

A

Dermatan sulfate

48
Q

San filippo syndrome

A

Heparan sulfate

49
Q

Morquio syndrome

A

Keratan sulfate

50
Q

Hypertrophic cartilage

A

Type. X

51
Q

Hexosamine unit of chondroitin sulfate

A

Galactosaminoglycan

52
Q

organic component of the bone

A

Osteocalcin

53
Q

Major proteoglycan in skin

A

Versican

54
Q

15-35% of the semen is secreted by the

A

Prostate gland

55
Q

Dominace of ceramide on the epidermal barrier

A

Atopic dermatitis

56
Q

Sever ey pain, blurring of vision and increase intraocular pressure

A

Glaucoma

57
Q

No corneal clouding

A

Hunter syndrome

58
Q

Structural proteins

A

Fibrillin
Collagen
Elastin