Special Populations

Question 1

Who would be considered special populations

Answer 1

Anyone below 18, older than 65, and those who are pregnant

Question 2

Teratogen

Answer 2

Agents that will disrupt normal development of a fetus or halt pregnancy

Question 3

Which trimester is the period of greatest danger?

Answer 3

First trimester due to massive cell formulation

Question 4

What is reduced (and why) regarding absorption in paediatrics

Answer 4

First pass effect because of immature liver

* this means that a drug given will have greater affect than to a person with a fully developed liver

Question 5

If the paediatric population has a undeveloped liver this means that the amount of protein will be?

Answer 5

Decreased

Question 6

What is metabolism like in the pediatric population?

Answer 6

With an immature liver there isn’t enough proper CYP enzymes to break down (metabolize) the drug therefore more drug will be going into the child’s system

Question 7

How does a kidney immaturity in the paediatric population affect secretion?

Answer 7

With undeveloped kidneys excretion because more difficult allowing the drug to stay in the body longer

Question 8

Who are the largest medicine consumers

Answer 8

Geriatric population

Question 9

Poly pharmacy

Answer 9

Individual is on multiple medications at a time