Spasticity Flashcards
1
Q
How does baclofen work ?
A
GABA analogue: works at spinal level and depresses CNS
2
Q
What are the side effects of baclofen ?
A
drowsiness, muscular hypotonia
3
Q
What are the withdrawal reactions of baclofen ?
A
hyperactive state, exacerbates muscle spasticity and precipitates autonomic dysfunction, hyperthermia, psychiatric reactions, convulsions.
Avoid abrupt withdrawal: gradually reduce dose over at least 1-2 weeks