Spasticity Flashcards

1
Q

How does baclofen work ?

A

GABA analogue: works at spinal level and depresses CNS

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2
Q

What are the side effects of baclofen ?

A

drowsiness, muscular hypotonia

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3
Q

What are the withdrawal reactions of baclofen ?

A

hyperactive state, exacerbates muscle spasticity and precipitates autonomic dysfunction, hyperthermia, psychiatric reactions, convulsions.
Avoid abrupt withdrawal: gradually reduce dose over at least 1-2 weeks

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