Spasticity Flashcards

1
Q

Tizanidine

A

MOA: α2 agonist
- enhances inhibition of muscle stretch reflex

AEs:
skeletal muscle weakness
hypotension
bradycardia
drowsiness
xerostomia

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2
Q

Baclofen

A

MOA: GABAB agonist
- enhances inhibition of muscle stretch reflex

AEs: skeletal muscle weakness (more than tizanidine)
dizziness
drowsiness
depression
fatigue

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