Indications for Anti-Anxiety Meds

Question 1

SSRIs

Answer 1

GAD
Panic
SAD
OCD
PTSD

*generally the agents of choice in the long-term treatment of anxiety-related disorders

Question 2

SNRIs

Answer 2

GAD
Panic
SAD

Question 3

TCAs

Answer 3

*Clomipramine

OCD

Question 4

BDZ

Answer 4

GAD
Panic

Question 5

Buspirone

Answer 5

GAD

Question 6

Paroxetine

Answer 6

GAD
Panic
SAD
OCD
PTSD

Question 7

Sertraline

Answer 7

Panic
SAD
OCD
PTSD

Question 8

Fluoxetine

Answer 8

Panic
OCD

Question 9

Fluvoxamine

Answer 9

OCD

Question 10

Escitalopram

Answer 10

GAD

Question 11

Benzodiazepines

Answer 11

• here anxiolytic effects (in addition to sedative-hypnotic effects)
• effective immediately
• all BDZs have anxiolytic effects but only some FDA-approved
• only recommended for short-term use (cause dependence)
• may be used while waiting for effect of SSRI

Question 12

Buspirone

Answer 12

• only anxiolytic activity (no sedative-hypnotic, anticonvulsant or muscle relaxant effects)
• least effective in the treatment of anxiety
  -most effective after 1-4 weeks of treatment

MOA: partial agonist at 5-HT1A receptors

AEs:
Dizziness
Non-specific chest pain