Sources of Variation Flashcards
-Changes in nucleotide sequence
-Alterations impossible to predict
-Mutation creates variation
Survival of the fittest (so that population becomes highly adapted to its environment
Mutations
Substitution in one base in a gene
-Transition, Transversion, Same Sense, Missense, Nonsense
Point mutation
- Purine to purine
- Pyrimidine to Pyrimidine
Transition
-Purine to Pyrimidine
Transversion
Codes for the same amino acid
Same Sense
Codes for different amino acid
Missense
A change in bases causes a stop codon-termination translation
Nonsense
Changes in the DNA sequence by either deletion or addition of bases
Frameshift mutation
Changes that alter, delete, disrupt, or rearrange the genes in the chromosomes
Structural Mutations
Aneuploidy and Euploidy
Numerical Changes
Addition/deletion of one or more chromosome in a normal set (genome)
Aneuploidy
Changes involving the whole genome or entire set of chromosomes
Euploidy