Sos- Consciousness Controlled Flashcards

1
Q

a capacity to direct attention and manipulate abstract ideas

A

Consciousness

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2
Q

wakefulness

A

arousal

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3
Q

how cortex responds to brainstem which controls arousal

A

awareness

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4
Q

keeps us at homeostasis of consciousness

A

brainstem

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5
Q

Anatomy of consciousness requires a network of _______

A

reticular formation + subcortical nuclei + cortex

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6
Q

route of info of ascending reticular activating system (ARAS)

A

reticular formation in the midbrain to thalamus to cortex

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7
Q

3D network of neurons (not a nucleus you can identify)

A

reticular formation

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8
Q

rostral pontine-caudal midbrain RF

A

MRF

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9
Q

regulates sleep, wakefulness, and arousal

A

reticular formation

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10
Q

Collect information about multiple sensory modalities – for example: pain, head snap

A

midbrain reticular formation (MRF) neurons

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11
Q

main pathway when dealing with arousal

A

midbrain to intralaminar/reticular thalamic nuclei to cortex

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12
Q

important nuclei for Alzheimer’s and reticular formation

A

Ach nuclei (cholinergic nucleus basalis of Meynert)

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13
Q

unconscious state that is arousable

A

asleep

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14
Q

unconscious state that is not arousable

A

coma

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15
Q

GCS < __ for coma/intubation

A

8

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16
Q

GCS of 13-14

A

mild impairment

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17
Q

GCS 9-12

A

moderate impairment

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18
Q

GCS of 3-8

A

severe impairment

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19
Q

____requires bilateral CNS damage

20
Q

punch to the face what two main things can happen

A

quick interruption of reticular formation (recovery)
diffuse axonal injury/coup/contrecoup

21
Q

GCS 3-8
everything slowed down
can’t breath on their own
>/= an hour
no voluntary movement

22
Q

bilateral damage that affects the brain
ex. uncal/central herniation

23
Q

2 main spots for coma lesions in brainstem

A

reticular formation
caudal midbrain- upper pons

24
Q

see corneas under eye lid going back and forth (normal during sleeping) abnormal in vegetative state

A

Roving eye movements

25
normal arousal to an awake state but unaware of self or environment
vegetative state
26
can breathe on their own brainstem reflexes intact reflexes present (but only in response to stimulation) present >/= 1 month (persistent ____)
vegetative state
27
Most things gone but can still do reflexes b/c spinal loops are still intact---just a reaction to the exam, they can’t elicit it EEG: flat line No activity on neuroimaging
brain death
28
brain death
29
vegetative state
30
What neurotransmitter is involved in ARAS or coma states or Alzheimers
Ach
31
most important nuclei of wakefuleness and found in nucleus basalis of meynert and important for alzheimers
cholinergic nuclei (Ach)
32
serotonin associated nuclei for wakefulness
rostral raphe n.
33
what inhibits ARAS (arousal system)
adenosine
34
what stimulates ARAS and blocks adenosine binding to receptor
caffeine
35
a normal suspension of ARAS activity
sleep
36
normal sleep decline with ____
age
37
good for repair, homeostasis get rid of breakdown products new memory formation
deep sleep
38
slow wave sleep and wide to narrow and not as deep as you progress in the sleep cycle
stages 3 and 4
39
awake and then right into REM sleep well-controlled with meds
narcolepsy
40
abnormal movements, sleep walking, talking, restless leg syndrome, sleep terrors (don’t remember) stress and lack of sleep can bring this out
non-REM parasomnias
41
sleep paralysis; hypnagogic hallucinations (right when you start to fall asleep---thought you saw mouse run across room)
REM parasomnia
42
can be from prion disease (destroys cells), normal to cognitive loss in 3 yrs happens in a short period of time (can happen with hunters eating raw meat)
fatal familial insomnia
43
trypanosomes (parasite); lives in blood; causes anemia and patient is sleepy all the time
African sleeping sickness
44
how does eating regulate sleep and arousal
ghrelin-orexin effects (brain shuts down while body is digesting food)
45
how does retina regulate arousal
light input that goes to suprachiasmatic nucleus (clock is set here) and then through sympathetics to pineal gland (melatonin)
46
increase in _______ will start you in sleep pattern and will continue increasing until cycle is over and you wake back up
melatonin