Broughton- Sleep Flashcards
a reversible behavioral state of perceptual disengagement from and unresponsiveness to the environment
sleep
a non-reversible behavioral state of perceptual disengagement from and unresponsiveness to the environment
coma
functions of deep sleep:
get rid of metabolic wastes (through glial cells)
memory consolidation
where our circadian clock resides
suprachiasmatic nucleus
melatonin released from where
pineal gland (from sympathetic stimulation from retina (ganglion cells)/suprachiasmatic nucleus)
deep sleep gets progressively _____ throughout the night
shorter
alpha waves
eye and muscle movement
awake
disappearance of alpha waves
onset of slow-rolling eye movements
theta waves and beta waves
N1 stage of sleep
persistent vegetative state
theta waves
sleep spindles and K complexes
N2 stage of sleep
deep sleep
high amplitude/slow wave
delta waves
peristent vegetative state
N3 stage of sleep
sawtooth pattern
theta waves
similar to awake state
eye movements (rapid)
sleep paralysis
REM sleep
large amounts of N3 sleep
children
decline in hours of sleep and deep sleep
as you get older
cataplexy
hypnagogic hallucinations
sleep paralysis
sleepiness
narcolepsy
sudden loss of muscle tone, usually triggered by laughter, anger surprise
cataplexy
very early dreaming at the onset of sleep (mouse running in the room)
Hypnagogic hallucinations
sensation of awakening from sleep and being unable to move
sleep paralysis
what is low in narcolepsy
orexin/hypocretin
what is high in narcolepsy
histamine
HLA allele DQB1*0602
narcolepsy
It appears that a person must be genetically susceptible to ____ and then be affected by some unknown environmental stimulus to trigger
narcolepsy
Usually treated with eugeroics (modafinil, soriamfetol, and pitolisant) or stimulants (methylphenidate/amphetamine)
narcolepsy
awake
N1
N2
N3
REM
