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Cell Bio Test 2 > Sorting 3 > Flashcards

Sorting 3 Flashcards

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1
Q

WHat two processes do we have when it comes to vesicles ?

A

Bud and Fuse

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2
Q

What type of protein is clathrin ?

A

A coat Protein

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3
Q

What determines the type of coat protein we get ?

A

Where the vesicle is sent

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4
Q

What is a great indicator that tells us where a protein is going, but doesn’t ultimately decide where it does end up ?

A

The Coat Protein

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5
Q

What does retrograde mean ?

A

Backwards

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6
Q

What does Anterograde mean ?

A

Forward

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7
Q

What does Copp 1 mean ?

A

Coat protein 1

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8
Q

What does COPP 2 do ?

A

Creates the vesicle that moves forward from the ERGIC and Golgi

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9
Q

COPP 2 transports from ?

A

ER —> ERGIC —> Golgi

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10
Q

What type of transport is clathrin ?

A

Golgi Transport

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11
Q

What are two kinds of proteins that are critical for vesicle budding ?

A

ARFs and RABs

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12
Q

What do both ARFs and RABs bind to ?

A

GDP/GTP

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13
Q

What is the general rule for G proteins

A

Inactive when bound to GTP

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14
Q

WHat is the general rule when G proteins are bound to GDP ?

A

They are active

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15
Q

What are RABs involved in ?

A

Involved in fusion

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16
Q

ARFs are involved with what ?

A

Involved with Budding

17
Q

What does vesicle formation involve ?

A

Involves a coat protein and a receptor protein

18
Q

What does ARF recruit ?

A

The receptor and Coat Protein

19
Q

WHat must happen in order for ARF to recruit and coat protein and a receptor?

A

It must be active

20
Q

What happens when vesicles are formed ?

A

ARF and calthrin go away, but we still have the receptor

21
Q

How many ARFs do we have ? How many receptors do we have for the amount of ARFS ?

A

We have 5 ARFs and 5 receptors

22
Q

We only receptors that are bound to the same what ?

A

Signal patches

Cell Bio Test 2 (5 decks)

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