Somatovisceral sensitivity II Flashcards
Nociceptor receptors are
free nerve endings located in most of the body
nociceptors are absent from
CNS and most of the viscera (kidney, liver, lungs, altough widespread tissue damage can cause slow aching pain in these areas)
nociceptor adaptation
very little, actually hyperalgesia
types of pain
fast and slow
fast pain time of response
0.1 s after a pain stimulus
fast pain feels like
needle, cutting, burning
fast pain is felt on
superficial but not on the deeper tissues
slow pain time of response
felt after 1 s or more and increases slowly during s and min
slow pain is associated with
tissue destruction
slow pain occurs
in almost any tissue
nociceptor groups
polymodal and mechanosensitive
polymodal nociceptor fibres
type IV or C
polymodal nociceptors respond to
mechanical, thermal, and chemical stimuli of high intensity
polymodal nociceptor pain
slow pain
mechanosensitive nociceptor fibres
Adelta or type III
mechanosensitive nociceptors respond to
mechanical stimuli of high intensity
types of nociceptors
- thermal pain stimuli
- chemical pain stimuli
- mechanical pain stimuli
thermal pain stimuli
receptors for burning hot
receptors for freezing cold
chemical pain stimuli
bradykin histamine serotonin Ach acids K+
mechanical pain stimuli
tissue disruption
ischemia
muscle spasm
excessive pressure
analgesia system of the CNS
contol system that suppresses pain impulses entering the CNS
Which areas are involved in the analgesia system of the CNS
- areas of the mesencephalon, upper PONS, and 3rd and 4th ventricle
- areas of the lower pons, upper and lateral medulla oblongata
- pain inhibitory complex in the dorsal horns of the spinal cord
visceral sensory signals are
very limited
mostly unconscious
related to the regulation of their activity
most consciously percieved visceral sensory signals
occur in response to intense mechanical or chemica stimuli = painful sensations
visceral pain is transmitted via
type IV fibres
how does visceral pain differ from superficial and deep pain
localised pain not very strong but diffuse can be very intense
no direct relation in between injury extent and pain intensity