Somatic Senses Flashcards
Physiology
What is a receptor?
any structure specialised to detect a stimulus - there are three types
Most simple receptor
cluster of free nerve endings, which can be myelinated and non-myelinated
pain, heat and cold are all mediated by this receptor design
Meissner’s corpuscle
mediates touch
consists of unmyelinated nerve endings in a connective tissue capsule
Pacinian corpuscle
unmyelinated nerve ending is surrounded by concentric layers of modified Schwann cells
Merkel disc
the combination of the enlarged myelinated axon terminals and the Merkel cell to which they are closely opposed in the epidermal layer
Ruffini’s corpuscle
consists of a bundle of collagen fibrils with a myelinated sensory axon branching between the fibrils, enclosed inside a flattened capsule
What is signal transduction?
the process of converting the stimuli into action potentials
What is the receptor potential?
The membrane potential charge when a receptor responds to a stimulus is called a receptor potential
What is adaptation?
when a continuous stimulus is applied, there is a decrease in action potential generation over time
Spatial summation?
occurs when, as the stimulus intensity increases, so does the number of individual neurones within a nerve generating an action potential
Temporal summation?
occurs when, as the stimulus intensity increases, so does the number of action potentials generated by individual neurones per unit time
Somatic Sense 1+2 (explain)
Touch and Pressure
- pressure is sustained touch
- stimuli is mechanical deformation, therefore receptors involved are referred to as mechanoreceptors
- light touch mediated by tactile (Merkel) discs and Meissner’s corpuscles
- Ruffini corpuscles detect heavy touch
- Pacinian and Ruffini corpuscles detect pressure
- receptors are found throughout the skin and in subcutaneous tissue, but are most numerous in skin of the fingers and lips
Somatic Sense 3 (explain)
Temperature
three types of receptors:
- cold receptors and warm receptors (thermoreceptors)
- pain receptors responding to extremes of temperature
warmth receptors are stimulated at temperatures greater than 30oC
heat-pain receptors are stimulated at above 45oC
cold receptors are stimulated at temperatures less than 45oC
cold-pain receptors are stimulated at less than 15oC
thermoreceptors are found in skin and other tissues including the cornea and urinary bladder
Somatic Sense 4 (explain)
Pain
two types of pain are often felt together e.g. pricking finger with needle
Fast pain:
creates a sharp, seemingly immediate sensation which is highly localised. It is conveyed to the spinal cord by thin, myelinated nerve fibres which exhibit a rapid conduction velocity (6-30m/s). These fibres are generally referred to as type Aδ fibres
Slow pain:
This type of pain creates, after a delay, a dull pain that’s hard to locate. It is conveyed to the spinal cord by unmyelinated nerve fibres with a slow conduction velocity (0.5-
2m/s). These fibres are generally referred to as type C fibres
K+ ions (released from damaged cells) excite nociceptors, and the intensity of pain felt can be directly related to the local increase in potassium ion concentration
- other chemicals exciting nociceptors are bradykinin and serotonin
Somesthetic Projection Pathways (explain)
Neuronal pathways which carry somatic signals to the parietal lobe of cerebral cortex
Somatic senses originating in the head region travel via the trigeminal nerve to an area of the parietal lobe referred to as the somatosensory cortex.
From areas below the head most signals travel via a tract referred to as the spinothalamic tract, signals
pass up the spinal cord, into the brainstem, the thalamus and from there to the somatosensory cortex.
Sensory fibres travelling via the spinothalamic tract cross over in the spinal cord, and as a result the cortex receives sensory information from the opposite side of the body.
The dorsal columns of the spinal cord carry proprioceptive signals and the sensation of fine touch.