solubility

Question 0

what is Henry’s law?

Answer 0

related to concentration effect:
at a constant temperature, the amount of a given gas dissovled in a given liqid is directly proportional to the partial pressure of the gas in equilibrium with the liquid.
–if you increase the partial pressure of the gas above the solution, it will DRIVE MORE GAS INTO the solution.

Question 1

what is the state of gas and liquid at equillibrium?

Answer 1

at equilibrium, the partial pressure of air in the gasseous phase is equal to the partial pressure of the gas in the liquid phase (also called tension)

Question 2

what does oil solubility have to do with anesthetic gasses?

2. what does the meyer overton rule state:

Answer 2

1. gasses are thought to be attracted to fatty acid chains in neuronal tissues which interferes wth synaptic function.
2. meyer-overton rule states that agents with highest oil solubility

Question 3

what is the fink phenomenon

Answer 3

Diffusion Hypoxemia: N2o is much more soluble than N2 so that N2O leaves the blood faster than N2 enters. As the N2O leaves, it dilutes the air so that the O2 concentration may be under 21% (leading to hypoxemia).

Question 4

sevoflurane:
mac:
vapor pressure:
blood gas solubility coeffecient:
oil gas solubility coeffecient:

Answer 4

Sevoflurane:
mac=1.8
vp=169
bgsc= 0.68
ogsc= 47

Question 5

desflurane:
mean alveolar concentration (mac):
vapor pressure (vp):
blood gas solubility coeffecient (bgsc):
oil gas solubility coeffecient (ogsc):

Answer 5

desflurane:
mean alveolar concentration (mac): 6.6
vapor pressure (vp): 669
blood gas solubility coeffecient (bgsc): .6
oil gas solubility coeffecient (ogsc):

Question 6

isoflurane
mean alveolar concentratins (mac):
vapor pressure (vp):
blood gas solubility coeffecient (bgsc):
oil gas solubility coeffecient (ogsc):

Answer 6

isoflurane
mean alveolar concentratins (mac):
vapor pressure (vp):
blood gas solubility coeffecient (bgsc):
oil gas solubility coeffecient (ogsc):