Soft Tissue Tumors Flashcards
What causes this type of lesion?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/170/776/q_image_thumb.jpg?1659443486)
Blunt trauma, usually to lower limb
(Myositis ossificans - note calcification of muscle in lower limb)
In which population would you expect to see this tumor?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/176/128/q_image_thumb.jpg?1659443497)
Young adult female
(Desmoid tumor in abdominal wal = note skeletal muscle + spindle cell proliferation w/o necrosis)
What may have caused this tumor?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/187/549/q_image_thumb.jpg?1659443500)
Minor trauma like thorn prick or insect bite
(Dermatofibroma - note dimpling of nodule)
Name the predominant cell type in this photomicrograph. Dx?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/162/375/q_image_thumb.jpg?1659443482)
Lipoblast; Liposarcoma
(Irregular nuclei + lipid vesicles in cytoplasm)
How would this lesion appear on histology?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/168/719/q_image_thumb.jpg?1659443486)
Fibroblast in tissue culture appearance/spindle cells in loose matrix
(Nodular fascitis - note well circumscribed mass on forearm of young adult)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/168/719/a_image_thumb.jpg?1659411031)
How would this tumor look on histology?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/191/488/q_image_thumb.jpg?1659443500)
Abnormal cells which recapitulate skeletal muscle +/- cross striations
(Rhabdomyosarcoma - notice involvement of the orbit in kid)
This tumor is most commonly seen in:
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/200/000/q_image_thumb.jpg?1659443504)
Reproductive age women (25-40%)
(Leiomyoma - well-circumscribed white tumor in uterus)
This is an example of the most common type of:
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/176/364/q_image_thumb.jpg?1659443497)
Superficial fibromatosis
(Dupuytren’s contracture - note the flexion of ring and pinky fingers with sparing of the thumb and index finger)
Where would this tumor most likely present?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/171/398/q_image_thumb.jpg?1659443487)
Lower limb
(Woven bone in granulation tissue = myositis ossificans)
How would this present clinically?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/166/713/q_image_thumb.jpg?1659443482)
Middle-aged to older adult with progressively growing soft, nontender mass
(Liposarcoma - notice the lipoblasts with bizarre nuclei and lipid vesicles in their cytoplasm)
Two ways this tumor can present?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/177/782/q_image_thumb.jpg?1659443499)
In tibia or femur in male in 4th decade of life = painful
In thigh or posterior knee in 35-55 year old = painless
(Fibrosarcoma - not the herringbone pattern of fibroblasts)
Complication of this type of tumor?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/200/288/q_image_thumb.jpg?1659443504)
Hemorrhagic necrosis if it outgrows its blood supply
(Leiomyosarcoma - cigar-shaped cells resembling smooth muscle with mitotic figures)
From where does this tumor arise? What happens with treatment?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/188/234/q_image_thumb.jpg?1659443500)
Dermis
High recurrence rate
(Dermatofibrosarcoma protruberans - notice umbilicated nodule; locally aggressive into subQ tissue)
What causes this lesion?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/169/323/q_image_thumb.jpg?1659443486)
Mesenchymal reaction to injury
(Nodular fascitis - note spindle cells in loose stroma)
What would you expect to see on histology of this lesion?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/177/256/q_image_thumb.jpg?1659443498)
Inclusion-like cytoplasmic condensation of actin
(Infantile digital fibromatosis)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/054/177/256/a_image_thumb.jpg?1659411031)