Soft tissue tumors Flashcards

1
Q

A 7yr old presented with a large swelling that has been progressively increasing for the past 3 yrs. Biopsy shows below. What’s the Dx?

A

Lipoma

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2
Q

A healthy, 53-year-old man presented with a small, soft, nontender mass of his right upper arm that progressively grew larger and firmer during the 6 weeks before evaluation. Micrograph show below. Dx?

A

Liposarcoma. Pic shows a lipoblast: very atypical cell with a bizarre nucleus and with vesicles of lipid in the cytoplasm

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3
Q

A 20 yr old comes in with history of a rapidly growing mass on the forearm. The mass is located in the subdermal fat and the biopsy is shown below. Dx?

A

Reactive Proliferans: Nodular Fasciitis

Histology depicts loose tissue cluture appearance

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4
Q

Male comes into the ER after suffering blunt trauma to his leg during a sporting event. The biopsy depicts woven bone that is well-formed at the periphery but immature bone is at the center . Xray below. Dx?

A

Reactive Proliferans: Myositis Ossificans

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5
Q

50 yr old male comes in with bilateral dupuytren contractures of both hands. Dx?

A

Superficial fibromatosis

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6
Q

You have a pt with a large locally aggessive tumor. Surgical exploration showed an encapsulated mass arising in the mesentery. Biopsy shows bland spindle cell proliferation with no mitotic figures and no necrosis. Dx?

A

Deep Fibromatosis

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7
Q

40 yr old male comes in with pain in his tibia. You get a biopsy shown below that demonstates herringbone pattern. Dx?

A

Fibrosarcoma

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8
Q

You suspect a fibrosarcoma in an 8yr pt. Biopsy confirms your Dx. The tumor has already metatasized. Prognosis?

A

Unlike fibrosarcoma in adults, the infantile form has an excellent prognosis, even in the face of metastatic disease at presentation, when treated with a combination of chemotherapy and resection.

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9
Q

You find a firm brown nodule on your pt’s arm. She said she previously had an insect bite in that location. If the skin over the nodule were squeezed it would form a dimple. Biopsy shown below. Dx?

A

Dermatofibroma aka fibrous histiocytoma.

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10
Q

What is this?

A

Dermatofibrosarcoma protuberans

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11
Q

You discover a tumor in your pt which histologically shows typical spindle cells arranged in a “storiform” pattern. There are also bizarre giant cels shown below. Dx?

A

Malignant fibrous histiocytoma

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12
Q

This tumor has a white fish flesh appearance grossly. Histology shows elongated strap cells (shown below) and are bizarre cells with abundant pink cytoplasm. Dx?

A

Rhabdomyosarcoma.

These are the bizarre cells with abundant pink cytoplasm

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13
Q

You discover a large tumor on the uterus of you pt. Biopsy shown. Dx?

A

Leiomyoma

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14
Q

You get a biopsy of a suspected leiomyoma. What does this biopsy tell you about the prognosis?

A

The biopsy shows typical cigar shaped nuclei which could be seen in leiomyoma or in leiomyosarcoma, but the in the middle of the image there are 2 mitotic figures within one field, a very worrisome observation. This would be typical of a lower grade leiomyosarcoma. Worse prognosis than leiomyoma

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