Social Considerations of Personalised Medicine Flashcards
Ethical, legal and social implications of human genome project
Fair use of genetic information Privacy and Confidentiality Psychological impact and stigmatization Reproductive issues Clinical Issues Testing Issues Conceptual and Philosophical Implications Health and Environmental Issues Commercialization of Products
issues with personal genetic testing
may learn unanticipated information, the knowledge is permanent
the laboratory process may result in errors.
If your data indicates that you are not at elevated genetic risk for a particular disease or condition, you should not feel that you are protected. The opposite is also true
Genetic research is not comprehensive.
not ethnically inclusive
future scientific research may change the interpretation of your DNA and the scientific community may show previous research to be incomplete or inaccurate
legal implication
insurance implication
what is NDAD
National DNA Database
Issues with using NDAD
indefensible and biased against ethnic minorities.
Only 50% men in population but 80% in NDNAD
what are incidental findings
These are findings that are the result of a clinical investigation that were not the original aim of the investigation
For example, a student volunteers for a MRI study of body fat distribution and a tumour is detected on their liver.
issues with incidental findings
NGS incidental findings often need further analysis
Not every predicted pathogenic mutation has an effect