SNS Agonists Flashcards
1
Q
Where are adrenoceptors found
A
On the effector organ of a sympathetic pathway using NA/A
2
Q
How do SNS agonists work (where are they mainly used)
A
Mimics the action of NA/A by stimulating adrenoceptors
-mainly used in the CVS, eyes and lung
3
Q
The activation of which adrenoceptors increase cAMP
A
ß1 and 2
4
Q
What is the effect of a1 on the cell
A
Activation of PLC, IP3 and DAG
5
Q
What is the effect of a2 activation on a cell
A
Decrease in cAMP
6
Q
Which adrenoceptors are more selective for NA
A
a1/a2
7
Q
Which adrenoceptors are more selective for A
A
B1/2
8
Q
Outline the metabolism of adrenaline
A
Tyrosine => DOPA => Dopamine
