SN2, SN1, E2, E1 Flashcards
Methyl substrate, protic solvent
SN2
Methyl substrate, aprotic solvent
SN2
Methyl substrate, strong base
SN2
Methyl substrate, bulky base
SN2
Primary substrate, protic solvent
SN2
Primary substrate, aprotic solvent
SN2/E2
Primary substrate, strong base
SN2/E2
Primary substrate, bulky base
E2
Secondary substrate, protic solvent
SN1/E1
Secondary substrate, aprotic solvent
SN2
Secondary substrate, strong base
E2/SN2 with E2 heavily favored
Secondary substrate, bulky base
E2
Tertiary substrate, protic solvent
SN1/E1
Tertiary substrate, aprotic solvent
SN1/E1
Tertiary substrate, strong base
E2
Tertiary substrate, bulky base
E2
Aryl halides _____ react in an SN2 reaction.
do not
Allylic vs. Vinylic halides in SN2
Allylic > vinylic
In a protic solvent, nucleophilic strength increases ______ the periodic table.
down
In an aprotic solvent, nucleophilic strength increases ____ the periodic table.
up
In what reaction can rearrangements occur, SN2 or SN1?
SN1
SN2 reaction rate depends on:
Concentration of substrate and concentration of nucleophile
SN1 reaction rate depends on:
Concentration of substrate
SN1 reactions are __molecular
uni
SN2 reactions are __molecular
bi
Solvolysis
When a solvent behaves as a nucleophile
For an SN1 reaction, is the retention product or inverted product favored?
Inverted product is favored
What reaction results in a racemic mixture, SN2 or SN1?
SN1
Anti-coplanar
Halogen and hydrogen are opposite each other
