Smoking Cessations & medications Kerr! Flashcards
For Smoking Cessations
List the Nicotinic Drugs
(memorize Generic Names)
Nicotine Patch Generic Name
-Nicodern CQ/Habitrol
Nicotine Gum Generic Name
-Nicorette
Nicotine lozenge
- Commit
Nicotine Inhaler
-Nicotrol lnholer
Nicotine Nasal Spray
- Nicotrol NS
Combination NRT therapy is : NICTOINE Patch + Nictoine (gum,, or spray, or lozenge)
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For Smoking Cessations
List Non-Nicotinic Drugs
(memorize the generic names)
- Buprorpion Sustained release (Buprorpion SR)
Can be used
w/NRT
Start 1-2 weeks
before quit date.
- Varenicline
Tartrate
Start 1 week
before quit date
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give simple prescription for FDA approved
nicotone drug
(easier to memorize 1 for the exam)
Nicotine Nasal Spray
Max dosage: 40 spray for a day
Duration: 6 months, tapers 6 week
give simple prescription for FDA approved
Non-nicotone drug
(easier to memorize 1 for the exam)
Varencline (tablet)
First 3 days: 0.5 mg a day (QD)
Next 4 days: 0.5 mg twice a day (TID)
after 7 days: 1 mg a day twice a day (TID)
Duration: No tapering needed, can take up to 6 months
What are the adverse effects of Nicotine Inhaler?
- Mouth and throat irritation
- Cough
• Side effem generally caused by
inappropriate use
What are the adverse effects of Nicotine Nasal
Spray?
- Nasal irrttation
- Sneezing
- Cough
- Teary eyes
What are the adverse effects of Nicotine Patch?
- local skin irritation
- insomonia
What are the adverse effects of Nicotine Gum?
- hiccups
- Dyspepsia
- mouth sorness
What are the adverse effects of Nicotine lozenge?
- Dyspepsia
- local irrttation mouth & throat
- Rarely causes coughing & hiccups
What are the adverse effects of Sustained release
bupropion (Zyban or Wellbutrin)?
- Insomnia
- Dry mouth
- Anxiety
What are the adverse effects of Varencline
tartrate Chontix ?
- Nausea
- Insomnia
- Abnormal dreams
Nicotine inhaler
Precautions/Contraindications
Reactive Airway Disease
Nictotine Nasal Spray
Precautions
Reactive Ariway diseases
Not recomended for pts with Chronic Nasal diseases ( nasal polyps & sinusitis)
Sustained Release Bupropion
Contraindications
- Seizure disorders
- Current use of bullrin or MAO inhibitor
- Eating disorder (bulimia, anorexia)
- Alcohol
- Head trauma
Moniter Blood presssure
Varenicline Tartlrate
Precaustions
- women breasfeeding should avoid
- pt with kidney problems -adjust dose
Nictoine Patch
Precutions
- Caution with 6 months of MI
Nictotine Gum
Precuations
- poor dentition
- maybe inappropriate for use for pts with compelete or partial denture (hard for them to chew)
Nictotine Lozenge
Precautions
- Xerostomia
TREATING TOBACCO DEPENDENCE:
A 2-PART PROBLEM
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Why is it so hard to quit: Nicotine addiction?
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What are the symptoms of Nicotine Withdrawal?
■Irritability/frustration/anger
■Anxiety
■Difficulty concentrating
■Restlessness/impatience
■Depressed mood/depression
■Insomnia
■Impaired performance
■Increased appetite/weight gain
■Cravings
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WHAT WORKS (5A’s)
- Ask about tobacco use and secondhand smoke exposure
- Advise to quit
- Assess interest in quitting
- Assist in quit attempt (referral and or pharmacotherapy)
- Arrange for a follow-up
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Is Treating Tobacco is within the
Scope of Practice of dentists?
Yes
•New York State Education Department has deemed that treating tobacco use is part of the scope of practice for dentistry, this includes prescribing smoking cessation products.
Nicotine replacement therapy (NRT)
&
FDA labeling
Is it Safe?
- NO safety concerns association with using more than one NRT
- NO significant safety concerns association with using NRT at the same time as a cigarettes
- Use for longer than 12 weeks is safe
Assist-Prescribe FDA-Approved Medications
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First Line Pharmacotherapy
in combatting smoking?
- Combination long- and-short acting Nicotine Replacement Therapy (NRT) (e.g., patch and gum, patch and inhaler)
- Varenicline alone
- Bupropion SR with NRT (long- or short-acting)
•What is NRT at the POC?
•Rationale for NRT at the POC
•Who will hand the patient NRT?
•What kind of NRT will be on stock?
•How to distribute NRT at POC?
•What is NRT at the POC?
–Distribution of a free starter pack of NRT to all smokers by clinic staff during the clinic visit
•Rationale for NRT at the POC
–NRT doubles the success rate of patients’ quit attempts
–Inconvenience of purchasing RNT or filling a prescription creates barriers
–The clinic is an opportune time to intervene
•Who will hand the patient NRT?
–Dental Students
•What kind of NRT will be on stock?
•Nicotine Patch, Gum, and Lozenge
•How to distribute NRT at POC?
–Take faculty-approved NRT request form to dispensary, where NRT is stored.
What is the The most effective treatment for
smoking cessation
a combination
of pharmacotherapy and counseling
PRIMARY HERPETIC GINGIOSTOMATITIS
medication
- OTC Magic Mouthwash
- OTC Analgesic Acetaminophen or Ibuprofen
- Rx Topical Anesthetic: Viscous 2% Lidocaine Solution
- Rx Antivirals: Acyclovir suspension
RECURRENT HERPES LABIALIS [PRODROME PHASE] – TOPICAL
- OTC Docosanol Cream
- Rx Acyclovir cream 5%
- Rx Penciclovir cream 1%
- Rx Acyclovir 5%/Hydrocortisone 1% cream
- Rx Acyclovir Buccal Tablets
RECURRENT HERPES LABIALIS [PRODROME PHASE] – SYSTEMIC
Rx Valacyclovir 1g tablets,
Rx Famiciclovir 500mg tablets
RECURRENT HERPES LABIALIS [VESICLE/CRUSTED PHASE]
Nothing you can do! Antivirals do not help at this stage
Helpful agents: Ice, Dessicants, L-lysine
RECURRENT INTRAORAL HERPES
Rx Topical Anesthetic: Viscous 2% Lidocaine Solution
MILD CANDIDIASIS
- Clotrimazole Troches
- Miconazole mucoadhesive buccal 50mg tablet to mucosal surface over Canine Fossa
- Nystatin suspension [100,000 u/mL] 4-6mL swish for >1 minute then swallowed, 4x/day - High sucrose content Caries risk
MODERATE-SEVERE CANDIDIASIS
- Fluconazole 100-200mg 1x/day for 7-14 days
- Itraconazole suspension 200mg 1x/day
- Posaconazole suspension
DENTURE STOMATITIS
- Nystatin on intaglio surface of denture when pt wears it
- Remove & clean denture at night
- Bleach 1:10
- Polident
- Microwave
- Reline denture/refit it
ANGULAR CHEILITIS
- Rx Clotrimazole cream 1%
- Rx Nystatin-Triamcinolone Acetonide Ointment/Cream, 15g tube, Apply to angles of mouth after meals & before bedtime
- Denture adjustment, reline, remake
CANDIDIASIS –IMMUNOCOMPROMISED, RECURRENT INFECTION
CHRONIC SUPPRESSIVE THERAPY
Fluconazole 100mg 3x/week
Clotrimazole 10mg troches 1 week/1 month
RECURRENT APHTHOUS STOMATITIS –ABORTIVE THERAPY: TOPICAL CORTICOSTEROIDS
DO NOT USE MORE THAN 2+ WEEKS
Clobetasol Ointment 0.05% (ultra potent)
Fluocinonide Gel/Ointment 0.05% (potent)
Triamcinolone Acetonide in Orabase 0.1% (intermediate)
RECURRENT APHTHOUS STOMATITIS – ABORTIVE/SUPPRESSIVE THERAPY: CORTICOSTEROID RINSE
-
Dexamethasone Elixir [EtOH base]
- 0.5mg/5mL, 600 mL, Swish and spit with 5-10mL for 5 minutes (up to)4x/day
-
Dexamethasone Solution [H2O base]
- 0.5mg/5mL, Swish and spit with 5-10mL for 5 minutes (up to) 4x/day
RECURRENT APHTHOUS STOMATITIS – SYSTEMIC CORTICOSTEROIDS [NOTE: SHORT-TERM USE ONLY TO GAIN CONTROL OF SEVERE DISEASE]
- Prednisone [Glucocorticoid & Immunosuppressant] 0.5mg/kg 1x/day for 1 week
ORAL LICHEN PLANUS – 1st LINE TOPICAL CORTICOSTEROIDS [NOTE: DO NOT USE 2+ WEEKS | A/E: Candidiasis]
Dexamethasone Elixir [EtOH base]
Dexamethasone Solution [H2O base]
Clobetasol 0.05%, 15g tube
Halobetasol Ointment 0.05%
ORAL LICHEN PLANUS – CALCINEURIN INHIBITORS [NOTE: DO NOT USE 2+ WEEKS | *BLACK BOX WARNING: CANCER]
- Tacrolimus Ointment 0.03% or 0.1%, 30g tube, Blot area dry, rub in thin film over areas 3x/day after meals & at bedtime
- Tacrolimus Solution 0.5mg/5mL
PEMPHIGUS VULGARIS
STAGE 1 TREATMENT: CONTROL
Systemic Corticosteroids
STAGE 2 TREATMENT: CONSOLIDATION
Immunosuppressants – i.e. CellCept [Mycophenolate mofetil] is steroid sparing - Must have no new lesions for 2+ weeks & 80% of lesions healed to get into “remission” stage - Can begin tapering steroids
STAGE 3 TREATMENT: REMISSION/MAINTENANCE
Rituximab
MUCOUS MEMBRANE PEMPHIGOID
Local Therapy [Local corticosteroids]
Dapsone, Tetracycline + Nicotinamide [NOT IMMUNOSUPPRESSIVE]
Low Risk: Oral mucosa only – Topical corticosteroid Clobetsol
High Risk: Ocular, Esophageal involvement – Systemic Corticosteroids Prednisone 1mg/kg
XEROSTOMIA/SJOGREN’S SYNDROME
Artificial Saliva
Biotene toothpaste & rinse
Orabalance gel
Pilocarpine 5-7.5mg 3x/day (tabletss)
Cevimeline 30mg 3x/day (tablets)