Smoking Cessation Quiz Flashcards
Certain pharmacologic properties are common to substances of abuse. Identify the property that is not one of the common properties.
A) Lengthy elimination half life
B) Rapid drug delivery to central nervous system
C) Enhance central action of dopamine
D) Tolerance or sensitization in vulnerable host
A
Identify the true statement:
A) Legal drugs cannot be abused
B) The majority of substance abuse is seen from using illegal drugs
C) Abuse of legal drugs is more prevalent than illegal drugs
D) Health care professionals are not susceptible to drug abuse
C
Identify the correct statement:
A) Tolerance is seen when adaptive responses to repetitive drug use are unopposed by the drug
B) Physical dependence refers to compulsive and uncontrolled use of a medication
C) Psychological dependence is seen when receptors are down regulated
D) Tolerance and physical dependence can be seen in patients who are not substance abusers
D
The fastest acting nicotine replacement formulation is the:
A) Nasal spray
B) Oral inhaler
C) Gum
D) Lozenge
A - serum nicotine concentrations peak 4-15 minutes after use of the nasal spray. Nicotine concentrations peak between 20-60 minutes for the other dose forms.
Patients report that relief of nicotine withdrawal symptoms is faster with the nasal spray than with other NRT formulations.
A recent trial of E-cigarettes was discussed in class. Identify the correct statement:
A) The trial found that the nicotine content of E-cigarettes was consistent
B) Overall the quit smoking rate for the e-cigarette, and for the nicotine patch groups was much less than expected. Thus the study was underpowered.
C) The trial found that nicotine delivery from e-cigarettes was consistent and reliable
D) The drop out rate was very low
B
Which statement is INCORRECT?
A) The cigarette is an ideal nicotine delivery device
B) Nicotine replacement plus counseling is an effective quit smoking strategy
C) Irritability, hostility, and depression are symptoms of nicotine withdrawal
D) The efficacy and safety of using electronic cigarettes for smoking cessation is well established
D
Which combination of nicotine replacement products was shown to be more effective than nicotine monotherapy?
A) Lozenge and nasal spray
B) Transdermal patch and any rapid acting formulation of nictoine
C) Gum and nasal spray
D) Gum and oral inhaler
B - combining a patch with a short acting NRT is as effective as varenicline monotherapy. NRT in combination with other drugs is also beneficial.
A 26 year old man has been applying a 14 mg transdermal nicotine patch every morning for about a week. He has managed to avoid smoking, but is having difficulty sleeping because of vivid dreams.
An effective option to improve his sleep is to:
A) Take zolpidem at bedtime
B) Remove the patch at bedtime
C) Discontinue the use of the patch
D) Decrease the dose of the patch
B - removing the patch at bedtime can minimize or even eliminate sleep disturbances
Effective smoking cessation pharmacotherapy should be continued for at least:
A) One month
B) 3-6 months
C) 6-9 months
D) 9 months to one year
B - treatment for up to one year was shown to be safe, however efficacy was the same as 6 months of treatment
A meta analysis concerning e-cigarettes and smoking cessation published in 2016 found that:
A) Use of e-cigarettes improves the ability to quit smoking
B) Use of e-cigarettes has no effect on the ability to quit smoking
C) Use of e-cigarettes impairs the ability to quit smoking
C
