Smoking Cessation

Question 1

NRT Patch

Answer 1

> 10 cigarettes/day: 21 mg/day x 4-6 weeks, 14 mg/day x2 weeks, 7mg/day x 2 weeks
< 10 cigarettes/day: 14 mg/day x 6 weeks, 7 mg/day x 2 weeks

Question 2

NRT Gum

Answer 2

1st cigarette < 30 min of waking: 4 mg strength
1st cigarette > 30 min of waking: 2 mg strength
Weeks 1-6: chew 1 piece every 1-2 hours
Weeks 7-9: chew 1 piece every 2-4 hours
Weeks 10-12: chew 1 piece every 4-8 hours
Max: 24 pieces/day

Question 3

NRT Lozenge

Answer 3

1st cigarette < 30 min of waking: 4 mg strength
1st cigarette > 30 min of waking: 2 mg strength
Weeks 1-6: 1 lozenge every 1-2 hours
Weeks 7-9: 1 lozenge every 2-4 hours
Weeks 10-12: 1 lozenge every 4-8 hours
Max: 5 lozenges every 6 hours; 20 lozenges/day

Question 4

NRT Nasal Spray

Answer 4

Each dose = 2 sprays (one in each nostril) = 1 mg of nicotine
Initial: 1-2 doses/hr for 6-8 weeks
Gradually decrease during weeks 4-6
Max:
5 doses/hour (10 sprays)
40 mg/day (80 sprays)

Question 5

Varenicline

Answer 5

Days 1-3: 0.5 mg tablet daily
Days 4-7: 0.5 mg tablet BID
Maintenance (day 8 and later): 1 mg BID
Continue x 11 weeks (total 12 weeks of tx)

Question 6

Bupropion SR

Answer 6

150 mg once daily for 3 days then increase to 150 mg BID
Doses should be 8 hours apart
Max: 300 mg/day