Internal Analgesics Flashcards
1
Q
Acetaminophen
A
Tylenol
MOA: decrease in COX activity leading to decreased prostaglandin synthesis
500-1000 mg Q4-6H PRN; max 4000 mg/day
2
Q
Aspirin
A
Bayer, Ecotrin, Bufferin
MOA: inhibit prostaglandin synthesis from arachidonic acid by irreversibly inhibiting both COX-1 and COX-2
325-1000 mg Q4-6H PRN; max 4000 mg/day
3
Q
Naproxen
A
Aleve
MOA: reversible inhibition of COX-1/-2 which decreases prostaglandin synthesis
220 mg Q8-12H PRN; max 660 mg/day
4
Q
Ibuprofen
A
Advil, Motrin
MOA: reversible inhibition of COX-1/-2 which decreases prostaglandin synthesis
200-400 mg Q4-6H PRN; max 1200 mg/day
5
Q
Phenazopyridine
A
Azo Urinary Pain Relief
190-199 mg PO TID with or after meals for no more than 2 days
