Smith LAIM Text QODs Flashcards
Delphiniums are second in importance only to locoweed as a source of economic loss due to plant toxicities in range animals of the United States. Select the correct toxic principle contained within the plant, mechanism of action and clinical signs seen in cattle that ingest the plant from the list below:
A. Pyrrolizidine alkaloid; inhibition of hepatocellular mitosis; weight loss, anorexia, diarrhoea, photosensitisation.
B. 3-methyl-indole; disruption of clara cell metabolism; acute respiratory distress and death.
C. Diterpenoid alkaloid; neuromuscular blockade via binding to nicotinic receptors; staggering, exciteability, basewide stance, bloat, death.
D. Ergot alkaloid; vasoconstriction; increased reproductive loss, necrosis of ears, lameness, reduced weight gain.
C. Diterpenoid alkaloid; neuromuscular blockade via binding to nicotinic receptors; staggering, exciteability, basewide stance, bloat, death.
Cyanogenic glycosides are contained within many plants that may be consumed by animals e.g. cherry trees, crabapples, eucalyptus, bracken fern. Which option below is true regarding cyanide toxicity in livestock?
A. Horses and pigs are more susceptible to cyanide toxicity than ruminants.
B. Chronic cyanide ingestion in Sorghum grass by pregnant horses and cattle can result in the birth of foals and calves with arthrogryposis.
C. Drying as hay or silage increased the cyanogenic potential of Bahai, Bermuda and Johnson grass.
D. Cyanotic membranes and chocolate brown blood are the hallmarks of cyanide toxicity.
B. Chronic cyanide ingestion in Sorghum grass by pregnant horses and cattle can result in the birth of foals and calves with arthrogryposis.
Many common pasture and crop plants fed routinely to cattle are capable of accumulating toxic levels of nitrates in the correct environmental conditions. Which of the following statements is true regarding nitrate toxicty?
A. Nitrites are converted to nitrates and ammonia in the rumen.
B. Excessive nitrate intake by pregnant mares can result in congenital hyperthyroidism in their offspring.
C. In ruminants, plants containing more than 5% nitrates (measured as KNO3) dry weight may be lethal. Sublethal effects are seen from feed containing 2.5% to 4.5% nitrates.
D. Treatment of nitrate toxicity includes removal from offending pasture, administration of cold water, vinegar and mineral oil via nasogastric tube and intravenous methylene blue.
D. Treatment of nitrate toxicity includes removal from offending pasture, administration of cold water, vinegar and mineral oil via nasogastric tube and intravenous methylene blue.
Select the option below in which the neurotoxic plant is correctly matched with its toxic principle and the disease induced by its ingestion.
A. Yellow star thistle; sesquiterpene lactone; chewing disease.
B. Perenial ryegrass; lolitrem B; bilateral stringhalt.
C. Locoweed; ptaquiloside; grass staggers.
D. False dandelion; phenytoin; epilepsy.
A. Yellow star thistle; sesquiterpene lactone; chewing disease.
Which of the following plants is NOT associated with cardiac and skeletal muscle pathology in large animals? A. White snakeroot (Eupatorium rugosum) B. Burrow weed (Isocoma pluriflora) C. Coffee senna (Senna occidentalis) D. Broomweed (Gutierrezia sarothrae)
D. Broomweed (Gutierrezia sarothrae)
The major liver fluke infecting ruminants in the USA is Fasciola hepatica. What degree of fluke burden is proposed to result in i) economic losses in infected herds, and ii) clinical disease in individual cattle?
A. 10-20 flukes/animal; >50 flukes/animal.
B. 10-50 flukes/animal; >100 flukes/animal.
C. >100 flukes/animal; >500 flukes/animal.
D. >40 flukes/animal; >200 flukes/animal.
D. >40 flukes/animal; >200 flukes/animal.
With regard to diagnostic tests for liver disease which of the following options is true?
A. An elevated SDH concentration is indicative of cholestasis.
B. AST is a liver specific enzyme.
C. Elevated direct (conjugated) bilirubin which constitutes >25% total bilirubin is a sensitive marker of cholestatic disease.
D. Bilirubinaemia is indicated by brown bubbles on the top of a urine sample after shaking.
C. Elevated direct (conjugated) bilirubin which constitutes >25% total bilirubin is a sensitive marker of cholestatic disease.
Which bacteria is responsible for causing Tyzzers Disease in foals? A. Clostridium piliforme. B. Echinococcus granulosus. C. Bacillus hepatica. D. Rhodococcus equisimillus.
A. Clostridium piliforme.
Several supplements are recommended for treatment of liver disease in dogs and humans. Which of the following options contains the correct pairing of a supplement/medication and its proposed mechanism of action?
A. Milk thistle; anti-fibrotic.
B. Acetylcystine; anti-oxidant, glutathione donor.
C. S-Adenosylmethionine; anti-inflammatory.
D. Pentoxyfylline; lyses biliary crystals.
B. Acetylcystine; anti-oxidant, glutathione donor.
Which of the following bacteria are responsible for causing Black Disease in ruminants? A. Clostridium perfringens type A. B. Clostridium sordhelli. C. Clostridium novyi type D. D. Clostridium novyi type B.
D. Clostridium novyi type B.
What is the most important management practice to employ in terms of prevention of Bacillary Haemoglobinuria in a cattle herd? A. Restrict access to bracken fern. B. Feed grain with 20ppm copper. C. Control liver flukes. D. Feed grain with 200ppm copper.
C. Control liver flukes.
What is the mechanism by which addition of ammonium chloride to the feed prevents urolithiasis in goats?
A. Decreases urine pH.
B. Encourages increased water intake.
C. Increases urine pH.
D. Increases urea production in the rumen.
A. Decreases urine pH.
Liver abscesses are found commonly in feedlot cattle at slaughter. What is the bacteria most frequently cultured from liver abscesses in cattle and what is its main virulence factor?
A. Trueperella pyogenes; haemolysin.
B. Fusobacterium necrophorum; leukotoxin.
C. Bacteroides fragilis; phospholipase C.
D. Clostridium difficile; exotoxin.
B. Fusobacterium necrophorum; leukotoxin.
Which of the following statements is true regarding the treatment of gastric ulcer disease in adult horses?
A. Trimethoprim sulfamethoxazole is recommended in treatment of EGGD.
B. Ranitidine is the treatment of choice for ESGD.
C. Omeprazole has equal efficacy in treatment of EGSD and EGGD.
D. Sucralfate is recommended in addition to omeprazole in initial treatment of EGGD.
D. Sucralfate is recommended in addition to omeprazole in initial treatment of EGGD.
What are the three phenotypic characteristics of horses and ponies with Equine Metabolic Syndrome?
A. Regional adiposity; history of laminitis; resting hyperglycaemia.
B. Obesity; insulin resistance; abnormal hair coat.
C. Generalised obesity or regional adiposity; insulin resistance; a predisposition towards laminitis.
D. Cresty neck score >3; BCS >6/9; familial history of laminitis.
C. Generalised obesity or regional adiposity; insulin resistance; a predisposition towards laminitis.
Which of the following horses is least likely to develop anhydrosis in Summer?
A. A 15 year old Morgan broodmare that lives in Nova Scotia.
B. A 6 year old Thoroughbred gelding used for eventing that lives in northern Queensland.
C. A 10 year old Quarter Horse mare used for barrel racing that has just moved to Florida.
D. A 12 year old Warmblood mare whose sire had anhydrosis that lives in Alabama.
A. 15 year old Morgan broodmare that lives in Nova Scotia.
Which of the following diets would be likely to cause Big Head (aka nutritional secondary hyperparathyroidism in a horse?)
A. A diet of oats and lucerne hay.
B. A diet of solely kikuyu grass.
C. A diet of mare and foal pellets and bermuda grass hay.
D. A diet of sweet feed, Senior pellets, rye grass and timothy hay.
B. A diet of solely kikuyu grass.
A miniature pony presents to you for treatment of retained foetal membranes. She is icteric and anorectic. You are concerned about metabolic disease in this pony so you run some bloodwork. Which of the following correctly matches a potential serologic abnormality and diagnosis in this pony?
A. Ketosis; serum beta-hydroxybutyrate concentration 337umol/L.
B. Hepatic lipidosis; serum triglyceride concentration 283mg/dL, bile acid concentration 28mg/dL.
C. Hyperlipaemia; serum triglyceride concentration 575mg/dL, serum clear.
D. Hyperlipidaemia; serum tryglyceride concentration 480mg/dL, serum clear.
D. Hyperlipidaemia; serum tryglyceride concentration 480mg/dL, serum clear.
Hypokalaemic myopathy can occur in post-partum dairy cattle being treated for ketosis as a consequence of treatment. Which of the following medications can induce hypokalaemia in ketotic cattle? A. Propylene glycol. B. Isofluprednone acetate. C. Dexamethasone. D. Triamcinolone acetonide.
B. Isofluprednone acetate.
A number of inherited immunodeficiency disorders have been reported in horses. Which of the following options correctly matches the disorder to the breed in which it is reported?
A. X-linked IgM deficiency; Fell Pony foals.
B. Combined variable immunodeficiency; Quarter Horse and Arabian yearlings.
C. Foal immunodeficiency syndrome; Caspian foals.
D. Severe combined immunodeficiency; Arabian foals.
D. Severe combined immunodeficiency; Arabian foals.
Which of the following antibiotics/antibiotic combinations are recommended for treatment of macrolide-resistant Rhodococcus equi pneumonia in foals? A. Doxycycline and rifampin. B. Enrofloxacin. C. Ceftiofur. D. Clindamycin and rifampin.
A. Doxycycline and rifampin.
Mycoplasma bovis is capable of causing multiple disease syndromes in cattle. Which of the following is not caused by Mycoplasma infection? A. Mastitis. B. Abomasitis. C. Tenosynovitis. D. Otitis.
B. Abomasitis.