Small RNAs in the Regulation of Biological Processes Flashcards
1
Q
What is c value?
A
size of genome
2
Q
Name the regulatory ncRNA and their function
A
microRNA - controls most gene translation
siRNA - viral defence
piRNA - germ cell production
long ncRNA - X chromosome inactivation
3
Q
What is lyonization?
A
one of the two x chromosomes in females is inactivated
4
Q
Recall the lyonization process
A
inactive X silenced by being packaged so it is a transcriptionally inactive structure - HETEROCHROMATIN, chosen X is random and last a lifetime
5
Q
Lyonization purpose
A
prevents female cells from having twice the X chromosome genes as male cells
6
Q
What controls lyonization?
A
Xist
7
Q
What is dicer essential for?
A
embryonic stages, allows stem cells to differentiate and stops multipoint stem cell depletion
