Small Intestine, Large Intestine and Rectum Flashcards
Steatorrhoea
Passing of stool that is pale, oily and floats on water. Caused by malabsorption of fat.
Gliadin
Fraction of gluten coeliacs are sensitive too
Tropical Sprue
Causes folate deficiency, responds to antibiotics
Giardia Lamblia
Water borne unicellular parasite, causes hypogammaglobulinaemia. Treated with metronidazole
Whipples disease
Caused by Tropheryma whippelii and presents with weight loss, abdominal pain and malabsorption. Very rare and effects skin, brain, joints and cardiac.
Myenteric Plexus
Made up of Meissener’s plexus (base of submucosa) and Auerbach’s plexus (between 2 layers of muscularis propria)
Inflammatory Bowel Disease
Chronic inflammatory condition resulting from inappropriate and persistent activation of the mucosal immune system driven by the presence of normal intra-luminal flora.
Skip lesions
Distribution of Crohn’s disease, in which random patches of disease are distributed throughout GI tract
Ischaemic Enteritis
Ischaemic lesions effecting any section of the small or large bowel due to occlusion of blood vessel.
Infarcted bowel
Occlusion of coeliac, superior mesenteric or inferior mesenteric leading to large transmural injury in bowel.
Radiation Colitis
Inflammatory reaction to abnormal irradiation. Impairs proliferation activity of cells in bowel. Mimics IBD in presentation.
Appendicitis
Acute inflammation of the appendix.
Adenoma of large bowel
Development of polyps in large bowel. Can be tubular, villous or tubulovillous.
Colorectal adenocarcinoma
Glandular tumour in large bowel, presentation varies depending on left or right sided.
Dukes’ Staging
Staging algorithm for colorectal cancer (A-D)
Ulcerative Colitis
IBD that features continuous inflammation of the rectum and potentially colon.
Crohn’s Disease
IBD that features skip lesions of inflammations anywhere in the GI tract.
Anal Crohn’s
Formation of fistula due to Crohn’s disease that protrudes out of anus
Calprotectin
White cell protein in leukocytes of bowel, can be detected in stool test as marker of inflammation
Sclerosing cholangitis
Disease of the bile ducts that causes strictures and can lead to liver cirrhosis. Associated with ulcerative colitis.