SM Psych/Mental Health Flashcards

1
Q

what tool is used to screen for depression?

A

PHQ-2

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2
Q

if PHQ-2 is positive, what should the provider do next?

A

give patient PHQ-9

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3
Q

what are the first line medications for depression (type of meds)?

A

SSRI
SNRI

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4
Q

what SSRI is approved for pediatric patients?

A

Fluoxetine

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5
Q

what are the adverse SE of depression medications (SSRI/SNRI)?

A

sexual dysfunction and weight gain

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6
Q

what herbal medication can be used to treat depression?

A

St. Johns Wort

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7
Q

what should we be thinking about when taking St Johns Wort with other SSRI medications?

A

Do not do that… SJW increases risk of serotonin syndrome if taken alongside SNRI or SSRI

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8
Q

Serotonin Syndrome:
-sx
-treated inpatient or outpatient?

A

-shivering, sweating, shaking (tremors); tachycardia and agitation
-refer to ED! emergency!

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9
Q

how long does it take for anti-depressant medications (ie SSRI/SNRI) to start to have an effect?

A

-4-6 weeks

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10
Q

what should the provider do if no sx relief in 4-6 weeks after starting SSRI/SNRI?

A

can increase dose or prompt further investigation
-ie fatigue - eval thyroid or any other underlying possible causes
-ie GI sx - common SE of SSRI/SNRI –> continue at same dose; takes a few weeks for GI SE to subside

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11
Q

after sx relief, how long do we allow patient to stay on medication?

A

after 6MO of being at therapeutic level, can try to taper off

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12
Q

suicide risk related to anti-depression medication
-what are the risk factors associated with increased suicide risk?
-are younger or older adults at higher risk?
-how should suicidal ideation be approached?

A

-male sex, hx of underlying psych disorders (ie depression), chronic pain, access to firearms, significant chronic/terminal
-older adults
-very straightforward

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13
Q

what antidepressant medication should not be prescribed to elderly patients? why?

A

-TCAs
-many anticholinergic SE

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14
Q

what antidepressants are safe in older adults?

A

Sertraline (Zoloft) and escitalopram (Lexapro); fairly low SE profile

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15
Q

what SSRI is most sedating?

A

Paxil (paroxetine)

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16
Q

what antidepressant medication should be avoided in patients with anxiety?

A

Prozac
-jitteriness is a known SE

17
Q

when are atypical antipsychotics used to treat depression?

A

used with atypical or refractory depression

18
Q

-when medications are utilized as atypical antipsychotics?
-SE of atypical antipsychotics

A

-olanzapine or Zyprexa, or quetiapine (Seroquel)
-wt gain, hyperlipidemia

19
Q

due to side effects associated with atypical antipsychotics, what lab work/data should be obtained?

A

lipid profile, blood glucose, and assess wt before giving prescription

20
Q

S/S of bipolar disorder

A

often has phases
-mania: few weeks - lack of sleep, racing thoughts, impulse purchases, very excited/easily distracted
THEN FLIPS
-can’t get out of bed, can’t do daily activities

21
Q

what is the tx for bipolar?

22
Q

what are things to consider regarding lithium use for bipolar tx?

A

-long term SE
-narrow therapeutic effect

23
Q

-S/S of lithium toxicity
-what organ system should be monitored while taking this drug long-term

A

-N/V, tremors, hyperactive reflexes, confusion, vision changes
-thyroid (when taking this med long-term); can lead to hypothyroidism

24
Q

what can lithium toxicity lead to (what disease)?

A

hypothyroidism

25
PTSD -S/S -TX
-nightmares, insomnia, hypervigilance, exaggerated startle response; stereotypical flashbacks (occasionally occurs) -meds and cognitive behavioral therapy are both first-line tx *SSRI's preferred
26
Seasonal affective disorders -def -cause -tx
-experiences depression routinely at same time every year; most common in winter -change of seasons affects the pt's circadian rhythm -meds, talk-therapy; exposure to light to reset circadian rhythm
27
-where are a bunch of medications metabolized in the body? -what helps to metabolize medications (what enzymes)? -what should the provider consider in regards to CYP450 and different substances/meds (effect on each other)?
-liver -CYP450 -different substances or meds can make CYP450 enzyme work faster, slower, or not at all
28
-what medications should be avoided when talking St Johns Wort simultaneously?
-avoid taking with other meds that inc serotonin (SSRIS) -avoid taking w/ drugs metabolized via CYP3A4 (one of the most important enzymes in CYP450 family) *SJW can dec efficacy of some of these drugs ie Warfarin, digoxin, psychiatric meds
29
how does the activity of the CYP2C19 enzyme vary?
-activity of this enzyme varies significantly across various populations = affects how person metabolizes certain meds, including pain meds and SSRIs
30
-what are some common SSRIs? -what conditions are SSRIs the first line treatment for therapy?
-paroxetine (paxil), escitalopram (lexapro), sertraline (zoloft), etc. -depression, OCD, PTDS, anxiety
31
-how do SSRIs work (patho)? -how do we know which SSRI to start with?
-increase serotonin in brain (serotonin affects mood) -trial and error
32
-how long does it take for SSRI to go into full effect? -what are the short-term SE of SSRI's? -what are the long-term SE of SSRI's? -what are the most common reasons patients stop taking SSRI's?
-4-6wks -N, diarrhea, HA, insomnia -decreased libido/sexual dysfunction, weight gain -decreased libido/sexual dysfunction, weight gain
33
-how is goal treatment reached when utilizing SSRI's? -what SSRI is also used to treat GAD? -which SSRI has a quick onset? -which SSRI's have a good safety profile?
-get patient to therapeutic dose, then stay there for 6 months; can then begin to taper off -escitalopram (lexapro) -escitalopram (lexapro) -escitalopram (lexapro)
34
-what SSRI is a good choice for OCD patients? -what SSRI is good to use for bulimic patients? -what SSRI is a good choice for elderly patients?
-paroxetine (paxil) -fluoxetine (prozac) -sertraline (zoloft)
35
-what is paroxetine use for off-label? -which SSRI can make patients feel jittery? -which SSRI do we worry most about weight gain and sedation?
-pre-menstrual disorders/menopause sx -fluoxetine (prozac) -paroxetine
36
-what population(s) should not be prescribed fluoxetine? -what is the black box warning regarding SSRI use?
-for those at risk for falls (elderly)/anxiety -increased risk of suicidal ideation