SM 156a - Diffusion and Gas Transport Flashcards
Some images and questions are borrowed from Dr. McCrimmon's lecture on Diffusion and Gas Transport (SM 156a)
1
Q
What is the chloride shift?
A
A rate-limiting chemical reaction that slows CO2 equillibration at the lung
- Increased HCO3- in the RBC activates the Cl-/HCO3- exchanger
- Cl- comes into teh cell
- H+ ions stay in the RBC, buffered by hemoglobin
- This slows down CO2 offloading to the lungs