Slides Ch 4

Question 1

What is the native conformation of a protein?

Answer 1

The biological function of a protein depends completely on its native conformation

Example sentence: Proteins must maintain their native conformation to carry out their specific functions.

Question 2

What are the shapes of proteins?

Answer 2

Proteins can have globular or fibrous shapes

Question 3

What are the four levels of protein structure?

Answer 3

1. Peptide group
2. Resonance of peptide bond
3. Peptide group is polar
4. Conformation of peptide group

Example sentence: Understanding the four levels of protein structure is crucial for studying protein function.

Question 4

What is the standard IUPAC definition of a dihedral angle?

Answer 4

The standard IUPAC definition of a dihedral angle involves the position of 4 atoms (A, B, C, D) and rotation around the central B-C bond

Source: http://www.proteinstructures.com/Structure/Structure/Ramachandran-plot.html, 9/17/2014

Question 5

What is the range of each dihedral angle in a Ramachandran plot?

Answer 5

Each dihedral angle can range from -180 to +180 degrees

Theoretically calculated