Clicker Flashcards
Can myoglobin perform the same function as hemoglobin?
No, myoglobin cannot release oxygen as well to the tissues.
© 2012 Pearson Education, Inc.
Does the heme of myoglobin bind oxygen at the same coordination site as hemoglobin?
No, because the heme of myoglobin binds oxygen at a different coordination site.
© 2012 Pearson Education, Inc.
Does 2,3BPG completely inhibit the binding of oxygen to myoglobin?
No, because 2,3BPG completely inhibits the binding of oxygen to myoglobin.
© 2012 Pearson Education, Inc.
Does myoglobin adopt a similar quaternary structure as hemoglobin in the blood?
Yes, in the blood myoglobin adopts a similar quaternary structure as hemoglobin and binds oxygen with positive cooperativity.
© 2012 Pearson Education, Inc.
Do both myoglobin and hemoglobin bind oxygen easily in the lungs?
Yes, because both bind oxygen very easily in the lungs.
© 2012 Pearson Education, Inc.
Is the native structure of a large protein the only stable 3-dimensional structure possible?
No, although the native structure has a low free-energy, there may be other conformations at other minima of free-energy.
© 2012 Pearson Education, Inc.
What effect does 2,3-bisphospho-D-glycerate (2,3BPG) have on hemoglobin?
Raises the effective concentration of oxygen in red blood cells.
© 2012 Pearson Education, Inc.
