sleep disorders Flashcards

1
Q

what are the possible functions of sleep try to name 6

A

conserve energy and effort, produce hormones, promote optimal performance, memory consolidation, mood regulation, augment immune system

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2
Q

at what stage do we enter sleep when healthy

A

normally sleep is entered through NREM

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3
Q

if sleep is entered through rem what can that suggest

A

If it is entered through REM, the person is

either depressed, sleep deprived or has narcolepsy

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4
Q

SWS sleep (slow wave) dominates what third of sleep

A

the first third

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5
Q

what third of sleep does rem predominate

A

last third

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6
Q

what percent of sleep does nrem and rem account for

A

nrem 75-80

rem is 20-25

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7
Q

what happens to heart rate in nrem sleep vs rem sleep

A

nrem hr regular

rem hr is irregular

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8
Q

what happens to BP in nrem vs rem

A

nrem regular

rem variable

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9
Q

what happens to RR in nrem vs rem

A

nrem regular

rem irregular

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10
Q

in nrem and rem how is the body responses to o2 and co2 change

A

nrem decreased,

rem significantly depressed

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11
Q

in nrem and rem what happens to muscle tone

A

nrem preserved

rem absent

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12
Q

what happens to brain o2 consumption and cbf

A

nrem reduced

rem increased

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13
Q

what happens to thermoregulation in rem and nrem

A
nrem homeothermic
rem poikilothermic (not maintained can vary)
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14
Q

what happens to penile tumescense and vaginal engorgement in sleep

A

nrem infrequent

rem frequent

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15
Q

As you get older what happens to the different sections of sleep

A

total sleep time decreases
less SWS
less homeostatic drive
indivudal naps more
Medical, psychiatric, social (e.g. loss of role, reduced social
interaction), environmental factors (e.g. nursing home placement,
reduced exposure to light) and polypharmacy may have an impact
on sleep
other illness can affect sleep

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16
Q

as you get older in abscense of pathology what happens to sws and rem sleep

A

sws decreases,

rem sleep shifts slightly earlier in the night

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17
Q

what is a circadian rhythm sleep disorder

A

sleep disorder that occurs/disrupts over the normal sleep wake cycle over 24hrs

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18
Q

name intrinsic primary sleep disorders

A

they alter the circadian timekeeping system, these disorders include dspd aspd non-24hr (blindness) , irregular (dementia)

19
Q

name extrinsic secondary sleep disorders which is a misalignment between extrinsic and intrinsic signal

A

shift work disorder

jetlag disorder

20
Q

what is delayed sleep phase disorder

A

▪ Sleep is out of phase with socially acceptable sleep-wake times,

21
Q

Clinical Features of DSPD

A

sleep is normal when they can sleep at their desired times. sleeping at conventional times causes sleep deprivation, insomnia or slipiness, unable to advance sleep.

symptoms will be chronic and persistent and may take drugs to help sleep and have a mental issue alongside

22
Q

how do you treat dspd

A

make sure the person wants treatment.

phottherapy, then melatonin, then cbt-I, then examine for pyschiatric co morbidity(may need to treat that)

23
Q

what is shift work disorder

A

Insomnia or excessive sleepiness with a recurring work schedule
that overlaps the usual time for sleep. normally one month of this can cause it, sleep log can support this

24
Q

what are the consequences of swd short term

A

mood disturbances, short day time sleeps, higher risk of accidents, gi problems

25
Q

what are long term risks of SWD

A

sleep disorder, mood disorder, cancer, drug abuse

26
Q

what advice would tyou give to someone to improve their shift pattern and help swd remembering that each individual is different

A

dont do more than 3 consec night shifts, distribute rest days, use power naps and caffiene, time meals and melatonin use, choose your own shifts and take regular shifts

27
Q

how much sleep do we get on average

A

The population mode is about 7.5 hours

28
Q

how much sleep do we need

A
depends on age
new born 12-18 hrs
3 months to 1 year 14-15
1-3 12-14 hrs
3-5 11-13
5-12 10-11
12-18 9 hrs
18+ 7-9 hrs
29
Q

How do I know I’m getting enough sleep? as too much or too little can be bad

A
You know you're getting enough sleep
when
for most of the day
most days
you have enough energy to do what you want
30
Q

what are some physiologic effects of sleep deprivation

A

irritability, cognitive impairment, impaired moral judgement, hallucinations, adhd symptoms, heart rate variability, heart disease, decreased reactions, tremours aches, t2dm, impaired immune

31
Q

how can sleep deprivation effect ind at work

A

Concentration - 68%

  • Handling stress - 65%
  • Listening - 57%
  • Relating to others - 38%
  • Solving problems - 57%
  • Decision making - 56%
32
Q

how does sleep deprivation compare with alcohol

A

“Drowsiness is similar to alcohol in how it compromises driving ability by reducing alertness
and attentiveness, delaying reaction times, and hindering decision-making skills”

17 hours of sustained wakefulness impairs performance =
0.05% BAC (0.08% is the legal UK limit)

33
Q

explain Hallucinations in Sleep Deprivation different types

A

▪ These occur at the sleep/wake transition
▪ Occur on going to sleep - Hypnagogic Hallucinations
▪ Occur on waking from sleep - Hypnopompic Hallucinations

Simple visual or auditory hallucinations (e.g. seeing shadows emerging from
the wall, hearing one’s name being called)
▪ Can be frightening, but insight is retained, and there is no delusional
expansion vs those hallucinations occurring in psychotic illnesses

34
Q

what are parasomnias

A

▪ Abnormal behaviours that occur in association with sleep
▪ Occur during :
▪ NREM sleep
▪ REM sleep

35
Q

why are parasomnias difficult to diagnose

A

▪ Diagnostically challenging
▪ Poor patient recall
▪ Limited history if no witness account
▪ Routine investigations are often normal

36
Q

name some sws or nrem parasomnias

A
▪ Confusional arousal
▪ Sleep Walking (somnambulism)
▪ Night terrors (pavor nocturnus)
▪ Sleep-related Eating Disorder
▪ Sexsomnia
37
Q

how can you treat night terrors a form of parasomnias

A

Education. CBT-I to stabilise sleep-wake patterns
▪ Scheduled awakening: 30min alarm method for children
▪ Keep the room safe; be aware of new environments
▪ Only wake fully if the episode lasts >45 mins
▪ Pregablin, Clonazepam

38
Q

how can youtry to diagnose nrem parsomnias

A

▪ Family History
▪ Exacerbated by sleep deprivation, stress, alcohol, OSA,
fever
▪ Patient is often amnesic for the event, but may have partial
recollection
▪ Partner may describe tearfulness or confusion

39
Q

how do you treat nrem parasomnias

A

Reassurance (benign)
▪ Education – CBT-I to improve sleep pattern
▪ Avoid triggers
▪ Safety
▪ Antidepressants (e.g. Fluoxetine, Trazadone)
▪ Clonazepam
▪ Melatonin

40
Q

what are rem parasomnias

A
second half of night
nightmares
reccurent sleep paraylysis
nocturnal groaning catathrenia
rem sleep behaviour disorder
41
Q

what signs present in REM sleep Behaviour Disorder

A
Often correlate with recalled vivid dreams –
usually aggressive
▪ May injure bed partner
second half of night
normally aged 50 onwards

normally males

42
Q

how are rbd and parkinsons associated

A

RBD is the most robust non-motor predictor of developing Parkinson’s
Disease, and it is a predictor of early cognitive impairment

43
Q

how do you diagnose rbd

A

Clinical history may be highly suggestive but a v-PSG would confirm the
diagnosis (catching an episode or REM without atonia)

44
Q

how do you treat rbd

A

patienbt education, stop medications that may be causing it, separate beds, clonazepam, melatonin