Sleep Disorders Flashcards

0
Q

Define sleep

A

An unconscious state from which the person can be aroused by sensory or other stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What successful treatment modalities exist for sleep disorders ?

A
Pharmacotherapy 
Behavioural therapy 
Continuous positive airway pressure (CPAP)
Dental appliances 
Surgical therapies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define coma

A

Unconsciousness from which the person cannot be aroused

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The neural metabolic theories of sleep pose the idea that sleep is for

A

Detoxification and regeneration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Cognitive theories of sleep function suggest that sleep is for

A

Learning and development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What stages of sleep do we go through

A
Awake
Drowsy 
1
2
3 (slow wave)
4 (slow wave) 
rem
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the EEG pattern of stage 1 sleep

A

Low voltage , mixed frequency
May be theta rhythm
Vertex sharp waves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe the EEG wave patterns of phase two sleep

A

Low voltage, mixed frequency
Sleep spindles
K complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe the EEG rhythms of stage 3 sleep

A

Delta rhythm
High amplitude waves
Low frequency
Prominent in frontal regions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe stage 4 sleep EEG pattern

A

Delta rhythm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the two stages of REM sleep

A

Tonic (desynchronised EEG and muscle Antonia)

Phasic (rapid eye movements- fast saccadic, myoclonus, dreaming)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sleep regulation mechanisms control

A

Sleepiness and wakefulness

Initiating & maintaining sleep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What part of the brain produces melatonin

A

Pineal gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What part of the hypothalamus is involved in circadian rhythm ?

A

Suprachiasmatic nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the epworth sleepiness scale

A

Various situations and scores for likeliness of falling asleep
ESS 18 severe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name two other subjective sleep questionnaires

A

Parkinson’s disease sleep scale (PDSS)

Restless leg syndrome rating scale

16
Q

What can be used to measure sleep activity in outpatients

A

Pulse oximetry
Ambulatory EEG
limited outpatient respiratory monitoring
Actigraphy

17
Q

What inpatient sleep tests can be conducted

A

Polysomnography

  • video EEG
  • respiratory monitoring
  • movement detection( EMG, Actigraphy )
18
Q

What is a mean sleep latency test

A

Measure of time to fall asleep (EEG) on four separate occasions
8 mins

19
Q

What is a maintenance of wakefulness test

A

Measure of ability to stay awake during 4 planned naps (EEG)

20
Q

Psychomotor vigilance test

A

Measure of reaction time taken to press a button in response to a stimulus

21
Q

What are the 5 main type of sleep disorders

A
Insomnia 
Hypersomnia 
Circadian rhythm disorders 
Parasomnias 
Movement disorders of sleep
22
Q

What is the overall prevalence of insomnia

A

30-48%overall

6% diagnosis

23
Q

What is insomnia

A

Inability to achieve and maintain sleep
Poor quality sleep
>1 month
Associated with fatigue , poor memory and concentration

24
Chronic insomnia is associated with what
Psychiatric disorders, alcohol drugs abuse, physical illness
25
What is the treatment for insomnia
Good sleep hygiene Short term prescription (4 weeks) hypnotic sedatives (ziplodem, temazepam ) CBT
26
What is the prevalence of sleep apnoea
Children 2-3% Middle Ages 5-7 Older adults >15
27
What are the clinical features of narcolepsy
``` Nocturnal sleep quality is poor Hypnagogic hallucinations Hypnopompic hallucinations (on waking up) Sleep paralysis Can occur with cataplexy ```
28
What is cataplexy
Sudden drop in muscle tone triggered by emotions Worsens with poor sleep and fatigue Consciousness is retained
29
What are the diagnosis criteria for narcolepsy
At least two : ESS> 11 Cataplexy HLA gene Night time sleep latency <8 mins
30
Narcolepsy is an intrusion of ....
REM Sleep In to wakefulness
31
What is the treatment for narcolepsy
Planned naps Stimulants Modafinil Methylphenidate Amphetamines
32
What drugs can be used to treat cataplexy
SSRIS : fluoxetine, paroxetine, sertraline and other antidepressants
33
Parasomnias can be either
Non REM or REM
34
Name four movement disorders of sleep
Restless leg syndrome Periodic limb movements of sleep Propriospinal myoclonus Rhythmic movement disorder of sleep
35
What is restless leg syndrome
Sensorimotor disorder of extremities Irresistible urge to move legs Relieved by movement of legs Worse towards evening
36
What are the type types of restless leg syndrome
Primary Ie genetics Secondary Ie iron deficiency , renal failure, drugs (TCAs and antipsychotics)
37
What treatments are available for restless leg syndrome
``` Iron Domaine agonists l dopa Clonazepam Pregabelin Gabepentin Opiates ```