Sleep Disorders

Question 1

What are some common types of Sleep disorders?

Answer 1

1) Insomnia
2) Restless leg syndrome
3) Narcolepsy

Question 2

Problems to address regarding sleep

Answer 2

1) Help falling asleep
2) Help staying asleep
3) Help falling and staying asleep

Question 3

Drugs to help fall asleep

Answer 3

1) Eszopiclone
2) Ramelteon
3) Zaleplon
4) Zolpidem

Question 4

Drugs to help stay asleep

Answer 4

1) Doxepin
2) Eszopiclone
3) Suvorexant
4) Zolpidem

Question 5

Drugs to help both falling asleep and staying asleep

Answer 5

1) Eszopliclone

Question 6

Hypnotics and Anti-depressants

Answer 6

1) Zolpidem (Ambien)
2) Zaleplon (Sonata)
3) Eszopiclone (Lunesta)

These are C4
They increase GABA at the benzodiazepine receptors
-High risk of respiratory depression

Question 7

Surovexant MOA

Answer 7

This is an orexin-receptor antagonist

-Contraindicated in narcolepsy

Question 8

What are the Melatonin Receptor Agonists?

Answer 8

1) Ramelteon (Rozerem)
2) Tasimelteon

-These can be used for longer term
-Not controlled

Question 9

Can benzodiazepines be used for sleep?

Answer 9

Short-term use only
LOT are considered safer in adults 65+

Question 10

What medications are used for Restless Leg Syndrome?

Answer 10

Dopamine Agonists:
1) Pramipexole
2) Ropinirole
3) Rotigotine

Also, Gabapentin enacarbil.