Sleep Flashcards

1
Q

Where does sleep activity originate from?

A

Reciclar formation on the brainstem

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2
Q

What type of neurons are in the recticular formation?

A

Setogenic

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3
Q

What does stimulation of the suprachiasmatic nuclei lead to?

A

Sleep promotion

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4
Q

What does damage to the SCN lead to?

A

Disrupt sleep

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5
Q

What controls melatonin release?

A

Suprachiasmatic nuclei

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6
Q

What’re inhibitory neurons from the hypothalmus stimulated by?

A

Light

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7
Q

Where do the inhibitory neurons from the hypothalamus act upon and inhibit?

A

The pineal gland

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8
Q

What’s orexin?

A

Excitatory neurotransmitter from hypothalamus needed for wakefulness

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9
Q

What’s narcolepsy caused by?

A

Defective orexin firing

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10
Q

What 7 things can you do to assess wakefulness in an individual?

A
Behaviour
General alertness
Speech patterns and content
Reading 
Writing 
Calculating 
Spell or count backwards
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11
Q

What’re the 4 types of wave patterns?

A

Alpha
Beta
Theta
Delta

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12
Q

When do alpha waves occur?

A

Relaxed awake state

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13
Q

When do beta waves occur?

A

In an alert awake state

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14
Q

When do theta waves occur?

A

Common in kids

Emotional stress, frustration and sleep in adults

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15
Q

When do delta waves occur?

A

Deep sleep

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16
Q

What happens in stage 1 of the sleep cycle?

A

Slow waves
Non REM sleep
Slow eye movements
High amplitude, low frequency theta waves

17
Q

What happens in stage 2 in the sleep cycle?

A

Eye movements stop
Frequency slows further
Sleep spindles occur

18
Q

What’re sleep spindles?

A

Clusters of rhythmic waves 12-14Hz

19
Q

What happens in stage 3 of the sleep cycle?

A

High amplitude very slow delta waves
Short episodes of faster waves
Spindle activity declines

20
Q

What happens in stage 4 in the sleep cycle?

A

Delta waves only

21
Q

What % of sleep is REM?

A

25%

22
Q

What stages are known as slow wave sleep?

A

1-4

23
Q

What stages are known as deep sleep?

A

3 and 4

24
Q

How often does REM sleep occur and how often does it last for?

A

5-30 mins every 90 mins

25
Q

What drug class increases the time spent in REM sleep?

A

Anticholinesterases

26
Q

What happens to HR,RR and metabolism in REM sleep?

A

HR+RR become highly irregular and metabolism increases

27
Q

What can be seen on an EEG during REM sleep?

A

Mimics beta waves

28
Q

What does sleep support?

A
Neuronal plasticity
Learning and memory 
Cognition 
Clearance of waste products from the CNS
Conservation of whole body energy
Immune function
29
Q

What’s the definition of insomnia?

A

A chronic instability to obtain the necessary amount or quality of sleep to maintain adequate daytime behaviour

30
Q

What’s chronic primary insomnia?

A

No identifiable psychological or physiological cause

31
Q

What’s temporary secondary insomnia?

A

Response to pain, bereavement or crisis

Usually short lived

32
Q

Name the 2 classes of drugs used to combat insomnia?

A

Barbiturates and benzodiazepines

33
Q

Night terrors vs nightmares

A

Nightmares=REM, wake and will remember it

Night terrors= seen in kids, occur in deep delta sleep, no recollection in the morning, thrashing and screaming

34
Q

What’s somnambulism?

A

Sleep walking

35
Q

When does somnambulism occur?

A

Non REM exclusively

36
Q

How can narcoleptic symptoms be interpreted?

A

An intrusion of REM sleep characteristics into the waking state